Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Cardio-metabolic and cytoskeletal proteomic signatures differentiate stress hypersensitivity in dystrophin-deficient mdx mice.
J Proteomics
December 2024
School of Biological Sciences, University of Canterbury, Christchurch 8041, New Zealand; Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, Australia; Department of Medicine, University of Otago, Christchurch 8014, New Zealand; Biomolecular Interaction Centre, School of Biological Sciences, University of Canterbury, Christchurch 8140, New Zealand; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1010, New Zealand. Electronic address:
Extreme heterogeneity exists in the hypersensitive stress response exhibited by the dystrophin-deficient mdx mouse model of Duchenne muscular dystrophy. Because stress hypersensitivity can impact dystrophic phenotypes, this research aimed to understand the peripheral pathways driving this inter-individual variability. Male and female mdx mice were phenotypically stratified into "stress-resistant" or "stress-sensitive" groups based on their response to two laboratory stressors.
View Article and Find Full Text PDFFirst report of acute, visceral, fatal toxoplasmosis in a naturally infected calf (Bos taurus).
Vet Parasitol
December 2024
Idexx Laboratories Hamilton, 20A Maui Street, Pukete, Hamilton 3200, New Zealand.
Cattle are considered resistant to clinical toxoplasmosis and viable Toxoplasma gondii is rarely isolated from bovine tissues. Currently, there is no histologically confirmed case of clinical toxoplasmosis in cattle. Here, the first confirmed case of acute toxoplasmosis in cattle is reported.
View Article and Find Full Text PDFArticle Synopsis
- The text discusses the importance of forecasting future health issues in the USA for effective planning and public awareness regarding disease and injury burdens.
- It describes the methodology for predicting life expectancy, cause-specific mortality, and disability-adjusted life-years (DALYs) from 2022 to 2050 using the Global Burden of Diseases framework.
- The forecasting includes various scenarios to assess the potential impacts of health risks and improvements across the country, focusing on demographic trends and health-related risk factors.
Respiratory syncytial virus burden in children under 2 years old in understudied areas worldwide: gap analysis of available evidence, 2012-2022.
Front Pediatr
November 2024
Vaccines and Antivirals Medical Affairs, Emerging Markets Region, Pfizer, Paris, France.
Article Synopsis
- A study reviewed RSV (respiratory syncytial virus) data from 149 countries across WHO regions to assess pediatric burdens from 2012 to 2022.
- A gap analysis revealed wide variations in hospitalization rates, mortality, and case definitions, with infants under 6 months at higher risk and needing longer hospital stays.
- Findings indicate significant regional differences in RSV impact and highlight the need for standardized data to better understand and address this health issue globally.
Modifiable Risk Factors for Subarachnoid Hemorrhage: Narrative Review With an Emphasis on Common Controversies and Epidemiologic Pitfalls.
Neurology
December 2024
From the Department of Neurosurgery (I.M.R., A.A., M.K.), University of Helsinki and Helsinki University Hospital, Finland; and The National Institute for Stroke and Applied Neurosciences (I.M.R., A.A.), Auckland University of Technology, New Zealand.
Given the relatively low incidence, high prehospital death rate, substantial geographical differences, and complex disease origin (combination of genetic and environmental risk factors), epidemiologic research on subarachnoid hemorrhage (SAH) and its risk factors is challenging. In practice, we are more or less forced to exploit compromised study designs and nonrepresentative data in such circumstances where it is almost impossible to gather comprehensive data through an optimal design. For example, hospital-based patient cohorts, administrative data repositories, and short-term population-based studies from small geographical regions are often used to research the incidence, case fatality, and risk factors of SAH, regardless of their inherent and self-evident limitations.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!