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Active internalization of the Penicillium chrysogenum antifungal protein PAF in sensitive aspergilli. | LitMetric
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Active internalization of the Penicillium chrysogenum antifungal protein PAF in sensitive aspergilli.

Christoph Oberparleiter Lydia Kaiserer Hubertus Haas Peter Ladurner Manfred Andratsch Florentine Marx

Antimicrob Agents Chemother

Department of Molecular Biology, University of Innsbruck, Innsbruck, Austria.

Published: November 2003

The Penicillium chrysogenum antifungal protein PAF inhibits the growth of various filamentous fungi. In this study, PAF was found to localize to the cytoplasm of sensitive aspergilli by indirect immunofluorescence staining. The internalization process required active metabolism and ATP and was prevented by latrunculin B, suggesting an endocytotic mechanism.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC253792PMC
http://dx.doi.org/10.1128/AAC.47.11.3598-3601.2003DOI Listing

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