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Mandibular anatomy of a new specimen of a prozostrodontian cynodont (Eucynodontia: Probainognathia) from the Upper Triassic of Brazil.
Naturwissenschaften
January 2025
Centro de Apoio à Pesquisa Paleontológica da Quarta Colônia Universidade Federal de Santa Maria (CAPPA/UFSM, Rua Maximiliano Vizzotto, 59897230-00, São João do Polêsine, Rio Grande do Sul, Brazil.
Prozostrodontia is a clade of probainognathian cynodonts that exhibit several morphological innovations later inherited by mammals. The earliest representatives of this group have been found in the Upper Triassic deposits of southern Brazil. In this study, we report the discovery of a probainognathian cynodont from the Buriol site (São João do Polêsine, Rio Grande do Sul, Brazil), Hyperodapedon Assemblage Zone (Late Triassic).
View Article and Find Full Text PDFEffectiveness of vapocoolant spray compared to eutectic lidocaine/prilocaine cream to enhance tolerance during intravenous catheterisation: a randomised controlled trial.
J Small Anim Pract
January 2025
Department of Clinical Science and Services, The Royal Veterinary College, University of London, Hatfield, UK.
Objectives: To determine if tolerance of intravenous catheterisation differs following the application of vapocoolant spray compared to lidocaine/prilocaine cream in dogs and cats.
Materials And Methods: A randomised controlled trial of client-owned dogs and cats requiring intravenous catheterisation was performed. They were randomly allocated to either have lidocaine/prilocaine cream applied to their skin 1 hour prior to intravenous catheterisation or a swab saturated with vapocoolant spray applied immediately prior to intravenous catheterisation.
Profiling of snoRNAs in Exosomes Secreted from Cells Infected with Influenza A Virus.
Int J Mol Sci
December 2024
Department of Virology, National Veterinary Research Institute, 24-100 Pulawy, Poland.
Small nucleolar RNAs (snoRNAs) are non-coding RNAs (ncRNAs) that regulate many cellular processes. Changes in the profiles of cellular ncRNAs and those secreted in exosomes are observed during viral infection. In our study, we analysed differences in expression profiles of snoRNAs isolated from exosomes of influenza (IAV)-infected and non-infected MDCK cells using high-throughput sequencing.
View Article and Find Full Text PDFComparative study of a commercial formula containing natural antimicrobials versus oral cephalexin or topical chlorhexidine-miconazole therapies for treating superficial pyoderma in dogs.
Vet Dermatol
January 2025
Department of Veterinary Medicine, School of Medicine and Life Sciences, Pontifícia Universidade Católica Do Paraná, Curitiba, Brazil.
Background: Chronic and recurrent pyoderma in dogs is driving a growing interest in natural antimicrobial products that offer minimal adverse effects and avoid antibiotic resistance.
Objectives: Evaluate the safety and efficacy of dermatological products with antimicrobial peptides and plant extracts, comparing them to chlorhexidine + miconazole and cephalexin therapy for superficial pyoderma in dogs.
Materials And Methods: Forty-five dogs with superficial pyoderma underwent clinical, cytopathological and microbiological diagnosis, and were randomly assigned to Group 1 (G1) treated with shampoo (two weekly baths) and lotion (twice daily on the affected areas) containing natural antimicrobials; Group 2 (G2) treated with two weekly baths using a therapeutic shampoo containing 2% chlorhexidine and 2.
Objective: To determine the effect of the administration of oral gabapentin (20 mg/kg) and trazodone (8 mg/kg) on the MAC of isoflurane in dogs.
Methods: 6 adult dogs (3 castrated males and 3 spayed females), aged 13.3 ± 1.
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