The aim of this work was to verify experimentally the reliability of 3D CT scan in measuring hepatic volumes. Eight livers were dissected from corpses. The referring liver volume was determined by measure of its hydric shift. The correlation coefficient R was 0.93 (p < 0.001) on 5 mm/5 mm 3D sections, 0.92 (p < 0.001) on 10 mm/10 mm 3D sections and 0.94 (p < 0.0006) on 5 mm/10 mm 3D sections. The paired t-test also showed a 5% risk correlation between the two measurements. Although in vivo imaging is slightly different from in vitro, 3D CT scan seems to be a reliable method to determine an hepatic volume without increased X-ray irradiation.
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Ann Thorac Surg Short Rep
March 2023
Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, Seoul, Korea.
Anomalous hepatic venous connection without other cardiac anomalies is a rare condition but does not have high clinical significance. We describe a patient in whom a portion of the left hepatic vein was directly connected to the left atrium, without intracardiac or extracardiac anomalies. A left-to-right shunt with tricuspid regurgitation and atrial fibrillation occurred from right atrial volume overload.
View Article and Find Full Text PDFAnn Thorac Surg Short Rep
June 2023
Department of Cardiovascular Medicine, Mayo Clinic Arizona, Phoenix, Arizona.
Background: The cardiovascular benefits of surgical repair in pectus excavatum (PEx) continue to be debated, with limited data supporting repair in adult patients. Hepatic vein flow is used to identify right-sided diastolic dysfunction in cardiovascular disorders, including tricuspid stenosis, cardiac tamponade, and constrictive pericarditis. This study evaluates the effects of cardiac compression on diastolic function (as assessed by hepatic vein flow patterns and velocities) before and after repair of PEx.
View Article and Find Full Text PDFEJNMMI Res
January 2025
Department of Radiology & Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, 3584 CX, the Netherlands.
Background: To study the feasibility of hepatobiliary scintigraphy (HBS) to improve selection and planning of patients with hepatocellular carcinoma (HCC) treated with holmium-166 (Ho)-microspheres radioembolization.
Results: Thirty-one patients with HCC were included and treated with Ho- radioembolization as part of a prospective phase 2 study. Twenty-seven patients were eligible for analysis, 67% had a cirrhotic liver morphology on imaging, 70% had multifocal disease and 51% had bilobar disease.
Alzheimers Dement
December 2024
Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Background: Obesity in midlife is a risk factor for developing Alzheimer disease later in life. However, the metabolic and inflammatory effects of body fat varies based on its anatomical localization. In this study, we aimed to investigate the association of MRI-derived abdominal visceral and subcutaneous adipose tissue (VAT and SAT), liver proton-density fat fraction (PDFF), thigh fat-to-muscle ratio (FMR), and insulin resistance with whole-brain amyloid burden in cognitively normal midlife individuals.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Herbert and Jackeline Krieger Klein Alzheimer's Research Center, Rutgers Biomedical and Health Sciences, Newark, NJ, USA.
Background: While body mass index (BMI) is widely used to gauge overall adiposity, its accuracy in older age has yielded inconsistent findings. Moreover, BMI does not account for variations in regional fat distribution, which may differ between sexes. This study aims to investigate whether regional adiposity plays a distinct role in impacting cognition and the volumes of AD-related brain regions in older adults with T2D enrolled in the Israel Diabetes and Cognitive Decline (IDCD) study.
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