We found that 2,2-difluoro-1,3-dimethylimidazolidine (DFI) is useful for not only fluorination but also dehydrating reactions. This dehydrating ability of DFI was applied to the syntheses of dihydrofurans (2) that are possible starting materials for various anticancer or antiviral drugs.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1081/NCN-120022607 | DOI Listing |
Publication Analysis
Top Keywords
22-difluoro-13-dimethylimidazolidine dfi
8
approach syntheses
4
syntheses 2'3'-dideoxy-2'3'-dehydronucleosides
4
2'3'-dideoxy-2'3'-dehydronucleosides 22-difluoro-13-dimethylimidazolidine
4
dfi dehydrating
4
dehydrating reagent
4
reagent 22-difluoro-13-dimethylimidazolidine
4
dfi fluorination
4
fluorination dehydrating
4
dehydrating reactions
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!