Applications of RNA interference for studies in DNA damage processing, genome stability, mutagenesis, and cancer.

Semin Cancer Biol

Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA.

Published: August 2003

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Article Abstract

RNA interference, discovered only five years ago, is an important system for the control of gene expression. It is also quickly becoming a valuable experimental tool as it allows investigators to knock down the level of expression of specific genes. In this paper, we review some applications of this technology for studies in DNA damage processing, genome stability, mutagenesis, and cancer.

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http://dx.doi.org/10.1016/s1044-579x(03)00044-0DOI Listing

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