State-related thalamic changes during antipsychotic treatment in schizophrenia: preliminary observations.

Psychiatry Res

Department of Psychiatry and Behavioral Science, University of Louisville School of Medicine, MedCenter One, Suite 340, 501 West Broadway, Louisville, KY 40202, USA.

Published: October 2003

Thalamic volumes and psychotic symptoms were assessed during psychotic exacerbation and during antipsychotic drug treatment. Reduction of psychotic symptoms (SAPS) during four weeks of treatment was highly correlated with volumetric expansion as measured by magnetic resonance imaging in both left and right thalamus [r(s)=0.75 and r(s)=0.82, respectively (both P<0.04)].

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http://dx.doi.org/10.1016/s0925-4927(03)00092-1DOI Listing

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