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Case report: osteo-articular infection in a patient with Chronic Granulomatous Disease.

Med Mycol Case Rep

December 2024

Université Paris Cité, Faculté de Médecine, APHP, Hôpital Necker Enfants malades, Service de Maladies Infectieuses et Tropicales, 149 rue de Sèvres, 75015, Paris, France.

is a recently reported yeast causing rare cases of fungemia. This species presents high minimum inhibitory concentrations (MICs) to fluconazole and echinocandins. We report an atypical metacarpophalangeal osteo-articular infection in a patient with Chronic Granulomatous Disease.

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Article Synopsis
  • Brucellosis is a rare but challenging disease to diagnose, especially when it involves the joints, and should be considered in patients with prolonged fever and joint pain.
  • A case study of a 41-year-old goat farmer highlighted her symptoms of low back and joint pain lasting four months, leading to a diagnosis confirmed by serological tests.
  • Early detection and treatment, including NSAIDs and antibiotics, resulted in complete symptom relief within four weeks, emphasizing the importance of detailed history and physical exams in diagnosing atypical cases.
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Article Synopsis
  • A case was reported of a woman in her mid-thirties with a long history of pulmonary TB who struggled with left heel pain and mobility issues due to tuberculous OM for three years, despite not showing typical systemic symptoms.
  • Early diagnosis and prompt anti-tubercular treatment are crucial for managing tuberculous OM, as most cases respond well to conservative care, while surgical options are reserved for severe cases.
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Article Synopsis
  • FDG-PET/CT is valuable for diagnosing infective endocarditis (IE) and detecting additional septic sites, with prior studies revealing osteoarthritic septic grafts (OASGs) in 19.1% of IE patients.
  • A larger study included 174 patients suspected of IE, finding OASGs in 27.6% of them, predominantly located in the spine, with 43.8% of cases being asymptomatic.
  • The presence of OASGs was linked to musculoskeletal pain and tricuspid valve involvement, indicating that early identification could influence antibiotic treatment and orthopedic management.
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Ankle impingement after extra-articular open fracture of the leg: Full arthroscopic treatment in the supine position.

Injury

June 2024

Department of Orthopaedic Surgery and Traumatology, Antoine Béclère Hospital, APHP, Paris-Saclay University, 157 rue de la Porte Trivaux, 92140, Clamart, France; Laboratory of Biomechanics, Bioengineering and Osteo-Articular Bioimaging B3OA, UMR7052, 10 avenue de Verdun, 75010, Paris, France.

Article Synopsis
  • The text discusses a surgical strategy for treating painful ankle impingements that can occur after high-energy trauma resulting in extra-articular open fractures of the leg.
  • The proposed method involves performing anterior and posterior arthroscopies primarily in the supine position, aiming to minimize complications and simplify the process.
  • Initial results from a small group of patients and cadaver tests suggest that the strategy is effective, with data supporting improvements in pain, mobility, and functional scores post-surgery.
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