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Exploring the landscape of congenital and idiopathic neutropenia in Moroccan children: a comprehensive retrospective analysis.
Immunol Res
January 2025
Laboratory of Clinical Immunology, Infectiology, and Autoimmunity (LICIA), Faculty of Medicine and Pharmacy of Casablanca, Hassan II University, Casablanca, Morocco.
Congenital neutropenia (CoN) is a heterogeneous group of inborn errors of immunity (IEI) characterized by recurrent infections and early onset of neutropenia (NP). This study aimed to investigate the demographic and clinical data of children with CoN and idiopathic neutropenia (IN) in Morocco. We performed a retrospective study of patients with CoN and analyzed the clinical and laboratory findings of patients with CoN and IN diagnosed between 1999 and 2018 in a clinical immunology unit of a large pediatric hospital.
View Article and Find Full Text PDFIntegrating natural product research laboratory with artificial intelligence: Advancements and breakthroughs in traditional medicine.
Biomedicine (Taipei)
December 2024
Million-Person Precision Medicine Initiative, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
The Natural Product Research Laboratory (NPRL) of China Medical University Hospital (CMUH) was established in collaboration with CMUH and Professor Kuo-Hsiung Lee from the University of North Carolina at Chapel Hill. The laboratory collection features over 6000 natural products worldwide, including pure compounds and semi-synthetic derivatives. This is the most comprehensive and fully operational natural product database in Taiwan.
View Article and Find Full Text PDFAn overview of intramedullary spinal cord metastases accompanied by a 2D intraoperative video.
Surg Neurol Int
December 2024
Department of Neurosurgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States.
Background: Metastatic intramedullary spinal cord metastases (IMSCMs) constitute <2% of spinal cord tumors. IMSCM is a late-stage manifestation of cancer with a highly variable presentation and poor survival rate. Here, we present an operative video involving gross total resection of an IMSCM (i.
View Article and Find Full Text PDF[Inflammatory bowel diseases in children and adolescents : An overview with particular attention to genetic testing].
Inn Med (Heidelb)
January 2025
Dr. von Haunersches Kinderspital, Kinderklinik und Kinderpoliklinik, Ludwig-Maximilians-Universität München, Lindwurmstr. 4, 80337, München, Deutschland.
Pediatric-onset inflammatory bowel disease (PIBD) is increasingly recognized in Germany. Patients with PIBD often present with more extensive and active disease. Clinical suspicion of IBD requires early initiation of the diagnostic work-up (e.
View Article and Find Full Text PDFChallenges of E-Waste Dismantling in China.
Toxics
November 2024
School of Public Health, Zhejiang Chinese Medical University, 548 Binwen Road, Hangzhou 310053, China.
Electronic and electrical products have deeply permeated all aspects of life, bringing a lot of convenience to individuals. However, the generation of e-waste after their end-of-life has resulted in serious risks both to the ecological environment and human health due to a lack of scientific and effective recycling and treatments. As two major types of components in e-waste, heavy metals and plastics can not only directly enter the human body via inhalation, ingestion, and skin absorption, but also accumulate in the human body indirectly through the food chain.
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