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Exploring perceptions and attitudes towards vaccines in a remote western DRC health zone.
Vaccine X
January 2025
Global Health Institute, Department of Family Medicine and Population Health, University of Antwerp, Antwerp, Belgium.
The Democratic Republic of the Congo (DRC) struggles with low full childhood vaccination coverage (around 50 %) and a high children-under-five mortality rate (79 deaths per 1000 live births). This situation is potentially exacerbated by vaccine hesitancy, which was identified by the World Health Organization (WHO) as one of the top 10 global health threats in 2019. To gain deeper insights into levels of vaccine confidence possibly influencing vaccination coverage, we explored perceptions and attitudes towards childhood and adult vaccines in Boende (Tshuapa province, western DRC), which experienced an Ebola outbreak in 2014 and hosted the EBL2007 Ebola vaccine trial (2019-2022).
View Article and Find Full Text PDFTreatment decisions in VRE bacteraemia: a survey of infectious diseases pharmacists.
JAC Antimicrob Resist
June 2023
Department of Clinical and Administrative Pharmacy, University of Georgia College of Pharmacy, 1000 Jefferson Street, USA.
Background: VRE infections increased in 2020. High-dose daptomycin (≥10 mg/kg) has shown mortality benefit over other regimens, though daptomycin resistance is increasing. Limited data exist on the practice patterns of ID pharmacists for VRE bloodstream infections (VRE BSIs).
View Article and Find Full Text PDFThe state of infectious disease training in Germany before introduction of the new board certification in internal medicine and infectious diseases: past experience and future expectations.
Infection
June 2023
Clinic for Pneumology and Allergology, Center of Sleep Medicine and Respiratory Care, Institute of Pneumology at the University of Cologne, Bethanien Hospital, Aufderhöher Str. 167, 42699, Solingen, Germany.
Article Synopsis
- The German Medical Association introduced a new board certification in Internal Medicine and Infectious Diseases (ID) and assessed current training experiences and curriculum expectations through a digital survey distributed among healthcare professionals.
- Out of 300 respondents, a significant portion (38.9%) had completed additional ID training, with concerns about the future recognition of their certifications, although most were satisfied with their training.
- A strong majority of participants agreed on the need to incorporate microbiology and antimicrobial stewardship into the new ID curriculum, and they highlighted the necessity for better childcare support and research commitment to attract more young professionals into the field.
Toll-like receptors in immunity and inflammatory diseases: Past, present, and future.
Int Immunopharmacol
June 2018
Children's Health Clinical Unit, School of Clinical Medicine, Faculty of Medicine, Mater Research, University of Queensland, ST Lucia, Brisbane, Queensland 4078, Australia; School of Biomedical Sciences, Faculty of Medicine, University of Queensland, ST Lucia, Brisbane, Queensland 4078, Australia. Electronic address:
The immune system is a very diverse system of the host that evolved during evolution to cope with various pathogens present in the vicinity of environmental surroundings inhabited by multicellular organisms ranging from achordates to chordates (including humans). For example, cells of immune system express various pattern recognition receptors (PRRs) that detect danger via recognizing specific pathogen-associated molecular patterns (PAMPs) and mount a specific immune response. Toll-like receptors (TLRs) are one of these PRRs expressed by various immune cells.
View Article and Find Full Text PDFPoint-of-Care Testing for Infectious Diseases: Past, Present, and Future.
J Clin Microbiol
August 2017
Department of Microbiology & Immunology, University of Nevada, Reno School of Medicine, Reno, Nevada, USA; DxDiscovery, Inc., Reno, Nevada, USA.
Article Synopsis
- Point-of-care (POC) diagnostics quickly provide valuable information for patient care during healthcare encounters, primarily using lateral flow immunoassays.
- Recent advancements in molecular diagnostics have made them suitable for POC use due to their speed, low cost, and user-friendliness.
- The focus on POC development is driven by the need to diagnose infectious diseases effectively in both well-developed and resource-limited environments, prompting innovation in existing and new diagnostic technologies.
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