AI Article Synopsis
- Preliminary injections of human TNF-alpha and IL-1 beta enhance guinea pigs' resistance to Coxiella burnetii.
- The effectiveness of these cytokines in boosting resistance is influenced by the dosage given.
- The timing of the injections also plays a critical role in how well the guinea pigs respond to the treatment.
Article Abstract
Preliminary injections of human recombinant tumor necrosis factor (TNF-alpha) and interleukin 1 (IL-1 beta) increases the resistance of guinea pigs to Coxiella burnetii. The increase of this resistance depends on the dose of cytokines and the time of their inoculation.
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