Cyclodextrins and emulsions.

Int J Pharm

UMR CNRS 8612, Physico-chimie, Pharmacotechnie, Biopharmacie, Faculté de Pharmacie, Université Paris-Sud, 5, Rue Jean Baptiste Clément, 92290 Châtenay Malabry, France.

Published: November 2003

This paper synthesises the literature on interactions between cyclodextrins (CD) and fatty acids and glycerides, and explains how these interactions allow the use of cyclodextrins to stabilise emulsions. An example of formulation with cyclodextrins is given which discusses the preparation of simple o/w emulsions, the addition of a model active ingredient, and the preparation of multiple emulsions in the absence of preformed surface active agents.

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Source
http://dx.doi.org/10.1016/s0378-5173(03)00384-3DOI Listing

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