The majority of legionellosis are caused by Legionella pneumophila, especially serogroup 1, the only diagnosed by Legionella urinary antigen test. The diagnosis of other serogroups and other Legionella species is based on culture and seroconversion. Sever cases are more frequently observed in immunocompromised patients and in nosocomial pneumonias. Each case must lead to look for the source of contamination, to detect other potential patients and permit environmental measures. Clinically and radiographically, the pneumonia is non specific except if suggestive gastro-enteric or neurologic symptoms are present. The diagnosis could be suspected in case of relative bradypnia or beta-lactamin resistance.
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BMC Pulm Med
January 2025
Department of Respiratory and Critical Care Medicine, Lishui Hospital of Traditional Chinese Medicine Affiliated to Zhejiang University of Traditional Chinese Medicine, No. 800 Zhongshan Road, Liandu District, Lishui, Zhejiang, 323000, China.
Background: Legionella pneumophila is an uncommon pathogen causing community-acquired atypical pneumonia. Acinetobacter baumannii is a major pathogen responsible for hospital-acquired pneumonia, but it rarely causes serious infections in a community setting. Without prompt and appropriate treatments, infection from either of these two pathogens can cause a high mortality rate.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Biological, Geological, and Environmental Sciences, University of Bologna, Bologna, Italy.
The identification and typing of bacteria are very expensive and time-consuming due to their growth times, and the expertise needed. MALDI-TOF MS represents a fast technique, reproducible with molecular approaches. This technique is still poorly applied in Legionella surveillance with estimation occurring only at the genus level.
View Article and Find Full Text PDFJ Water Health
December 2024
Laboklin GmbH & Co KG, Steubenstraße 4, 97688 Bad Kissingen, Germany.
Antimicrobial resistance is an emerging problem in hospitals and long-term healthcare facilities. Early detection of susceptibility pattern changes in pathogenic bacteria can prevent treatment failures. Therefore, this study chose to investigate the antibiotic susceptibility situation of isolates from hospitals and long-term healthcare facilities in Southern Germany.
View Article and Find Full Text PDFAnn Med
December 2024
Emergency Department, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Objectives: Detection and diagnosis of () pneumonia is often overlooked due to conventional methods limitations and similarity to other atypical community acquired pneumonia (CAP). Using mNGS, we aimed to distinguish psittacosis from legionellosis for early pneumonia diagnosis and better prognosis.
Methods: Thirty-seven patients diagnosed with atypical CAP were enrolled in this retrospective study, including 14 pneumonia and 23 () pneumonia.
Pathogens
October 2024
Department of Medical Microbiology and Infectious Diseases, University of Manitoba, 745 Bannatyne Ave., Winnipeg, MB R3E 0J9, Canada.
is an underdiagnosed and underreported etiology of pneumonia. serogroup 1 (LpSG1) is thought to be the most common pathogenic subgroup. This assumption is based on the frequent use of a urinary antigen test (UAT), only capable of diagnosing LpSG1.
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