It is difficult to repair tears of the meniscus at the white zone by suturing. We considered that there might be an optimal tissue welding temperature when thermally welding the meniscal white zone, so we conducted a thermal welding experiment using bovine and human menisci. The samples prepared after thermal welding were investigated by measuring the tensile strength, analyzing the histological findings of the welded portion and the meniscal parenchyma, and conducting biochemical analyses. In the experiment using human menisci, histological findings were investigated using transmission electron microscopy (TEM). As the findings on the welded tissue in the white zone of the bovine meniscus indicated positive results at 63 degrees C and 69 degrees C, the experiments using human meniscal white zone were conducted at these two temperatures. The highest tensile strength after thermal welding of the human meniscal white zone was 101.4 +/- 2.6 g/cm(2) at 63 degrees C. Although there were no significant differences in the amount of pyridinoline per unit collagen weight [Pyr/Hpr (%)] in the human meniscus after thermal welding between the control group and various temperature groups (55 degrees C, 63 degrees C, 69 degrees C, 75 degrees C), the amount of pyridinoline per unit of collagen weight tended to decline as the welding temperature increased. According to the TEM findings, the internal structure of the nuclei of the cells was preserved in the 63 degrees C group, whereas cells were denatured inside the nuclei in the 69 degrees C group. They exhibited necrosis, making cell regeneration difficult. Therefore, it seems feasible that thermal welding at 63 degrees C can repair tears in the human meniscal white zone.
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http://dx.doi.org/10.1007/s00776-003-0688-9 | DOI Listing |
Acta Odontol Scand
January 2025
Private Practice, Kristianstad, Sweden.
Aims: Little attention has been paid to patients' perception of function and esthetics with single dental implants. The aim of this study was therefore to describe patient-reported function and esthetic outcomes in single dental implants. A second aim was to study the objective esthetics in single dental implants.
View Article and Find Full Text PDFVasc Health Risk Manag
January 2025
Department of Cardiology, the Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, People's Republic of China.
Objective: An association between white blood cell count (WBC-C) before percutaneous coronary intervention (PCI) and prognosis has been established in patients undergoing PCI. However, the effect of WBC-C after PCI on the long-term prognosis of patients with unstable angina pectoris (UA) is unclear.
Methods: A retrospective cohort study was conducted in 1811 consecutive patients with UA.
Ann Neurol
January 2025
Neuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Objective: The aim of this study was to explore the microstructural dynamics of the subventricular zone (SVZ) with aging and their associations with clinical disability and brain structural damage in pediatric-onset multiple sclerosis (MS) patients.
Methods: One-hundred and forty-one pediatric-onset MS patients (67 pediatric and 74 adults with pediatric-onset) and 233 healthy controls (HC) underwent neurological and 3.0 T MRI assessment.
BMC Ophthalmol
January 2025
Department of Ophthalmology, Linkou main branch, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Background: While vaccination remains crucial in mitigating the impact of the COVID-19 pandemic, several ocular adverse events has been reported, including Acute Zonal Occult Outer Retinopathy (AZOOR) complex.
Case Presentation: A 31-year-old female presented declined best corrected visual acuity (BCVA) and flashes in both eyes three days following second recombinant mRNA COVID-19 vaccine (Moderna). Fundus autofluorescence (FAF) illustrated speckled hyper-AF lesions surrounding right eye torpedo maculopathy site and hyper-AF lesions in the left macula.
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