There have been many advances in HIV counseling, testing, and referral over the past ten years. One of the most recent advances is the United States Food and Drug Administration's (FDA) approval of a rapid test. As a result of the availability of rapid diagnostic testing for HIV, practices regarding testing and counseling need to be updated, particularly in time-sensitive situations in which rapid results are crucial.
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Biologic Downstaging Observed With a Pulmonary Collision Tumor.
Ann Thorac Surg Short Rep
September 2023
Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California.
Collision tumors are a rare entity in which 2 distinct neoplastic cellular populations invade each other and coalesce to form a single focal lesion. This case report describes a pulmonary collision tumor emerging from the rapid progression of 2 large-cell carcinoma lesions of the lung, including 1 nodule with clear cell features and another with basaloid features. The collision of these 2 histologically rare nodules resulted in the biologic downstaging of disease.
View Article and Find Full Text PDFTime-efficient HPLC Validation Methodology for the Qualitative Analysis of 68Ga PSMA-11 in Routine Clinical Usage under Isocratic Method.
Indian J Nucl Med
November 2024
Department of Nuclear Medicine and Molecular Imaging, Homi Bhabha Cancer Hospital and Mahamana Pandit Madan Mohan Malaviya Cancer Centre, Tata Memorial Centre, Homi Bhabha National Institute, Varanasi, Uttar Pradesh, India.
Background: Prostate-specific membrane antigen (PSMA) has shown to be a promising agent for prostate cancer imaging under PET-CT. With the automation in radiolabeling with 68Ga, using iTG 68Ge/68Ga generator, it has helped introduce various new diagnostic agents and achieve good manufacturing practices (GMP) simultaneously. However, before any radiopharmaceutical is put into clinical usage, it should always be checked for its radiochemical purity and other quality parameters before injecting in the patient.
View Article and Find Full Text PDFFractional flow reserve measurement using dynamic CT perfusion imaging in patients with coronary artery disease.
Radiol Adv
October 2024
Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.
Purposes: The objective was to evaluate the accuracy of a novel CT dynamic angiographic imaging (CT-DAI) algorithm for rapid fractional flow reserve (FFR) measurement in patients with coronary artery disease (CAD).
Materials And Methods: This retrospective study included 14 patients (age 58.5 ± 10.
Lung Transplantation for Familial Diffuse Pulmonary Ossification.
Ann Thorac Surg Short Rep
September 2024
Department of Thoracic Surgery, Kyoto University Hospital, Kyoto, Japan.
We report 3 cases of extremely rare familial idiopathic diffuse pulmonary ossification, 2 of 3 received lung transplantation and the other is listed for lung transplantation. The clinical courses of family members varied greatly, and rapid deterioration could occur; therefore, early and close examination is recommended for transplant registration. During transplantation, the lungs appeared and felt exactly like a "pumice stone" and could not collapse, and good visual field was not easily obtained.
View Article and Find Full Text PDFHighly Selective AIEgen-Based "Turn On" Fluorescent Imaging for Inflammation Detection.
Luminescence
January 2025
State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan, China.
Hypochlorous acid (HClO) is released by immune cells in the immune system, and it helps the body fight off infections and inflammation by killing bacteria, viruses, and other pathogens. However, tissue damage or apoptosis may also be induced by excess HClO. On this basis, we designed the probe TPE-NS by choosing tetraphenylethylene (TPE) as the luminescent unit and dimethylthiocarbamoyl chloride as the recognition site.
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