AI Article Synopsis
- The study investigates the impact of thermal-induced ablation on the ability to perform sentinel node biopsies in breast cancer patients.
- Twenty-one patients who underwent sentinel node biopsy after microwave ablation were analyzed, revealing that 68% showed tumor necrosis, and mapping was successful in 91% of cases.
- The results suggest that sentinel lymph node mapping remains effective even after prior localized tumor ablation.
Article Abstract
Background: Breast cancer tumor ablation as part of a multimodality approach in the treatment of breast cancer is the subject of recent interest. This study was conducted to determine if the ability to perform sentinel node biopsy was impaired after thermal-induced ablation of breast cancer.
Methods: We studied patients who had sentinel node biopsy after preoperative focused microwave phased array for breast cancer ablation.
Results: Twenty-one patients with T1-T2 breast cancer and clinically negative axilla underwent wide local excision and sentinel node biopsy guided by blue dye and sulfur colloid. Surgery was done an average of 17 days after microwave ablation. Fifteen of 22 patients (68%) had histologic evidence of tumor necrosis. Sentinel lymph node mapping was successful in 19 of 21 patients (91%). Axillary metastases were detected in 42% of cases.
Conclusions: This study documents successful sentinel lymph node mapping for patients treated with antecedent local tumor ablation using focused microwave phased array ablation.
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| http://dx.doi.org/10.1016/s0002-9610(03)00267-8 | DOI Listing |
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