301 adolescents aged 15 to 16 years (158 girls and 143 boys) were examined for caries under standardized conditions during the fall and spring terms of 1987/88. Clinical examinations, performed by two calibrated examiners were supplemented with posterior bite-wing radiographs which were assessed by one of the examiners. The mean DFT and DFS scores (incipient lesions included) were 9.8 and 19.4, respectively. The mean DFS score (dentin lesions+restorations) was 6.4. On average 1.9 surfaces had frank cavities or recurrent lesions and 13 surfaces had incipient lesions. Occlusal surfaces contributed 75%, approximal 21% and bucco-linqual 4% to the manifest component of the DFS score (4.8, 1.4 and 0.2 surfaces, respectively). 3% of the incipient lesions were found occlusally, 51% approximally and 46% bucco-linqually (0.4, 6.6 and 5.9 surfaces, respectively). Only 3% of the participants were completely free from caries, whereas 9% had no dentin lesions or restorations. 15% of the subjects with the highest caries prevalence averaged 15.8 dentin lesions or restorations. A tendency towards polarization of low and high caries prevalence groups was observed. Totally 91% of the individuals had occlusal caries, 82% approximal and 76% bucco-lingual, whereas dentin lesions or restorations had 88%, 42% and 14%, respectively.
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J Endovasc Ther
January 2025
Division of Angiology, Department of Medicine II, Medical University of Vienna, Vienna, Austria.
Purpose: To report the occurrence of acute postrenal kidney failure caused by external ureteral obstruction after iliac venous stent placement.
Case Report: A 73-year-old male patient presented with a chronic swelling and feeling of heaviness of his right leg. The presence of venous thrombosis was excluded by duplex ultrasound (DUS).
Curr Atheroscler Rep
January 2025
Department of Ophthalmology, NYU Langone Medical Center, New York, USA.
Purpose Of Review: Cardiovascular disease (CVD) is a leading cause of preventable morbidity and mortality globally, and retinal imaging modalities (old and new) are being explored as noninvasive tools to predict latent atherosclerosis and cardiovascular disease. This review focuses on the emerging promise of fundoscopy, optical coherence tomography (OCT), and optical coherence tomography angiography (OCTA) in CVD prognostication.
Recent Findings: High-quality studies have established the utility of vessel-based parameters and discrete conditions diagnosable via fundoscopy in subclinical atherosclerosis detection or CVD prediction.
PLoS One
December 2024
Evandro Chagas National Institute of Infectious Disease, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil.
Objective: To compare the spatio-temporal distribution of cutaneous leishmaniasis (CL) cases with mucosal leishmaniasis (ML) cases in the state of Rio de Janeiro (RJ) between 2001 and 2011.
Method: The incidence rates (IR) of CL and ML were calculated for the cases notified between 2001-2011 in the Information System of Notifiable Diseases for Rio de Janeiro (RJ, and for the municipalities of Rio de Janeiro and Angra dos Reis, with georeferencing and construction of thematic maps. A negative binomial regression model was used to assess the temporal dependency between CL and ML.
Am J Clin Pathol
December 2024
Department of Pathology and Laboratory Medicine, Cleveland Clinic Foundation, Cleveland, OH, United States.
Objectives: Urothelial carcinoma in situ (CIS) with early papillary formation is terminology sometimes used to suggest incipient high-grade papillary urothelial carcinoma (PUC) but may lead to confusion between true CIS and lateral flat spread of PUC.
Methods: It remains unclear how pathologists and urologists interpret this scenario, so a survey was circulated to 68 pathologists (group 1 = 28 academic genitourinary pathologists; group 2 = 17 pathologists with a self-reported genitourinary focus; group 3 = 23 pathologists self-reported as not genitourinary specialists) and 32 urologists.
Results: Regarding atypical urothelial lesions that appear mainly flat but contain possible papillae, group 3 was more likely to label this as CIS compared with groups 1 and 2 (35% for group 3 vs 13% for groups 1 and 2), while groups 1 and 2 more often adopted another descriptive diagnosis, such as "CIS with early papillary features" (38% for groups 1 and 2 vs 13% for group 3).
Eur J Neurol
January 2025
Spinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Background: Magnetic resonance imaging may suggest spinal cord compression and structural lesions in degenerative cervical myelopathy (DCM) but cannot reveal functional impairments in spinal pathways. We aimed to assess the value of contact heat evoked potentials (CHEPs) in addition to MRI and hypothesized that abnormal CHEPs may be evident in DCM independent of MR-lesions and are related to dynamic mechanical cord stress.
Methods: Individuals with DCM underwent neurologic examination including segmental sensory (pinprick, light touch) and motor testing.
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