The acyl trypsin was prepared by use of an inverse substrate, which is comprise of a photoresponsive 4-phenylazobenzoyl moiety. The acyl group in acyl trypsin has been shown to isomerize from trans-form (4t-trypsin) to cis-form (4c-trypsin)/from cis-form to trans-form by irradiation of UV-vis light. The deacylation rate of the cis-form (4c-trypsin) has been shown to be 18.6 times faster than that of the trans-form (4t-trypsin).

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2003.07.013DOI Listing

Publication Analysis

Top Keywords

acyl trypsin
12
deacylation rate
8
inverse substrate
8
trans-form 4t-trypsin
8
photoregulation deacylation
4
acyl
4
rate acyl
4
trypsin derived
4
derived photoresponsive
4
photoresponsive inverse
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!