Objective: To study the therapeutic action of decoction of Smilax china L. on adjunctive arthritis(AA) mouse and its mechanism.
Methods: To observe the change of secondary inflammation, thymus and spleen weights, T cell subgroup, B cell, NK cell.
Results: The decoction (90, 180 g.kg-1) intragastric injection (ig) could significantly inhibit AA mouse's secondary inflammatory swelling, reduce thymus and spleen weights, decrease CD4/CD8, but had little influence on B Cell.
Conclusions: The decoction has therapeutic action by regulating cell-mediated immunity, but has little effect on humoral immunity.
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