The oxamate group in the title compound, C(10)H(11)NO(3), is almost coplanar with the phenyl ring because of intramolecular hydrogen-bonding interactions, and the structure can be described as an anilide single bonded to an ethyl carboxylate group. The supramolecular structure is achieved through intermolecular hard N-H...O and soft C-H...X (X = O and phenyl) hydrogen-bonding interactions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1107/s0108270103017554 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Steroids and steroid-like compounds alter the ion permeability of phospholipid bilayers distinct interactions with lipids and interfacial water.
Phys Chem Chem Phys
January 2025
School of Chemistry and Molecular Biosciences, University of Queensland, St Lucia QLD 4072, Australia.
Steroids are organic compounds found in all forms of biological life. Besides their structural roles in cell membranes, steroids act as signalling molecules in various physiological processes and are used to treat inflammatory conditions. It has been hypothesised that in addition to their well-characterised genomic and non-genomic pathways, steroids exert their biological or pharmacological activities an indirect, nonreceptor-mediated membrane mechanism caused by steroid-induced changes to the physicochemical properties of cell membranes.
View Article and Find Full Text PDFA computational study of the ternary mixtures of NaPF-EC and choline glycine ionic liquid.
Phys Chem Chem Phys
January 2025
Institute of Science and Technology, Federal University of São Paulo, 12247-014, São José dos Campos, São Paulo, Brazil.
This study investigates the structural and dynamic properties of ternary mixtures composed of NaPF, ethylene carbonate (EC), and the ionic liquid choline glycine (ChGly), with a focus on their potential as electrolytes for supercapacitors. The combination of NaPF-EC, known for its high ionic conductivity, with the biodegradable and environmentally friendly ChGly offers a promising approach to enhancing electrolyte performance. Through molecular simulations, we analyze how the inclusion of small concentrations of ChGly affects key properties such as density, cohesive energy, and ion mobility.
View Article and Find Full Text PDFThe interaction between meiosis-expressed gene 1 (MEIG1) and Parkin co-regulated gene (PACRG) is a critical determinant of spermiogenesis, the process by which round spermatids mature into functional spermatozoa. Disruption of the MEIG1-PACRG complex can impair sperm development, highlighting its potential as a therapeutic target for addressing male infertility or for the development of non-hormonal contraceptive methods. This study used virtual screening, molecular docking, and molecular dynamics (MD) simulations to identify small molecule inhibitors targeting the MEIG1-PACRG interface.
View Article and Find Full Text PDFJunctional Role of Anionic Domain of Mussel Foot Protein Type 4 in Underwater Mussel Adhesion.
Biomacromolecules
January 2025
Department of Chemical Engineering, Pohang University of Science and Technology, Pohang 37673, Republic of Korea.
Mussel byssi form a robust underwater adhesive system, anchoring to various surfaces in harsh marine environments. Central to byssus is foot protein type 4 (fp-4), a junction protein connecting collagenous threads to proteinaceous plaque. This study investigated an anionic plaque-binding domain of fp-4 (fp-4a) and its interactions with cationic foot proteins (fp-1, fp-5, and fp-151 as model substitutes for fp-2) and metal ions (Ca, Fe, and V).
View Article and Find Full Text PDF1,4,5-Trisubstituted-carboxylated 1,2,3-triazoles: an unconventional class of ribonuclease A inhibitors.
Org Biomol Chem
January 2025
Department of Chemistry, Indian Institute of Technology Kharagpur, Kharagpur 721 302, India.
The "catalytic triad" present at the active site of ribonuclease A (RNase A) is responsible for the cleavage of the 5'-phosphodiester bond; amino acid residues His12, Lys41 and His119 constituting this triad provide a positively charged environment at the physiological pH. Based on docking studies, 1,4,5-trisubstituted-carboxylated 1,2,3-triazoles (1,4,5-TTs) were identified as a new class of RNase A inhibitors. Therefore, two different groups of 1,4,5-TTs, functionalized with carboxylic acid groups, were synthesized by reacting pre functionalized butyne-1,4-diol derivatives with several aryl/alkyl azides under solvent and catalyst free conditions.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!