While holding a complex neuropsychological testing of 60 patients with disseminated peritonitis, we encountered a problem of a secondary reactive somatopsychosis due to metabolic encephalopathy. It is noteworthy, that the severity of psychoemotional disorders expectedly progressed depending on a degree of endogenous intoxication. Such circumstance must be duly considered in composing and implementing an intensive care scheme for the discussed patients' category.
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Sci Adv
January 2025
State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300353, People's Republic of China.
Acute alcohol intoxication could cause multiorgan damage, including nervous, digestive, and cardiovascular systems, and in particular, irreversible damage to the brain and liver. Emerging studies have revealed that the endogenous multienzymatic antioxidant defense system (MEAODS) plays a central role in preventing oxidative stress and other toxicological compounds produced by alcohol. However, few available drugs could quickly regulate MEAODS.
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Department of Psychiatry and Medical Psychology and Research Institute, Research and Innovation Program for the Development of MU-PLOVDIV (SRIPD-MUP), Creation of a Network of Research Higher Schools, National Plan for Recovery and Sustainability, European Union (NextGenerationEU), Medical University Plovdiv, Vassil Aprilov str. 15a, 4002 Plovdiv, Bulgaria. Electronic address:
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