Tunable, monochromatic X-rays: an enabling technology for molecular/cellular imaging and therapy.

J Cell Biochem

Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, 1161 21st Avenue South, Nashville, Tennessee 37235-2675, USA.

Published: October 2003

Pulsed, tunable, monochromatic X-rays hold great potential as a cellular and molecular probe. These beams can be tuned to the binding energy of orbital electrons in atoms, making them extremely useful in diagnostic k-edge imaging and Auger cascade radiotherapy. Their wide tunability makes them ideal for the performance of various techniques as disparate as protein crystallography and three-dimensional, compressionless, monochromatic mammography. Since only the frequency best suited to the task at hand is used, radiation exposure to patients or animals is exceedingly low when compared to standard X-ray techniques.

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http://dx.doi.org/10.1002/jcb.10632DOI Listing

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