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Nonconvulsive status epilepticus in patients under intensive care: Should we view epilepsy as a sleep disorder?
Epilepsia
January 2025
Epilepsy Unit, Gui de Chauliac Hospital, Montpellier, France.
Nonconvulsive status epilepticus (NCSE) was initially described in patients with typical and atypical absence status epilepticus (ASE) characterized by states of confusion varying in severity and in focal epilepsies with or without alteration of consciousness. Continuous EEG monitoring of critically ill patients has further refined the classification of NCSE into two main categories: with coma and without coma. Hypnotic, soporific or somniferous epileptic seizures do not exist.
View Article and Find Full Text PDFCeftriaxone encephalopathy in a very elderly dialysis patient.
CEN Case Rep
December 2024
Department of Nephrology and Hypertension, Saitama Medical Center, Saitama Medical University, 1981 Kamoda, Kawagoe, Saitama, 350-8550, Japan.
Ceftriaxone is widely used clinically but it can potentially cause ceftriaxone encephalopathy in individuals who are on dialysis. We describe ceftriaxone encephalopathy in a dialysis patient. The 87-year-old Japanese woman had a 9-year dialysis history.
View Article and Find Full Text PDFAn 8-Year 5-Month-Old Boy with a Basal Ganglia Lesion with Triphasic Waves on Electroencephalogram.
Actas Esp Psiquiatr
October 2024
Department of Pediatrics, West China Second University Hospital, Sichuan University, 610017 Chengdu, Sichuan, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, 610017 Chengdu, Sichuan, China.
Background: Triphasic waves (TWs) on electroencephalograms (EEGs) have predominantly been observed in adults, often associated with Creutzfeldt‒Jakob disease and metabolic encephalopathy. However, TWs have also been linked to various nonmetabolic and structural abnormalities. Additionally, reports of TWs in children are rare.
View Article and Find Full Text PDFReversible ifosfamide-induced encephalopathy with bursts of triphasic waves responsive to levetiracetam.
Arq Neuropsiquiatr
November 2024
Universidade Federal do Paraná, Complexo Hospital de Clínicas, Departamento de Neurofisiologia, Curitiba PR, Brazil.
Acoustically responsive scaffolds: Unraveling release kinetics and mechanisms for sustained, steady drug delivery.
J Control Release
October 2024
Department of Radiology, University of Michigan, Ann Arbor, MI, USA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA; Applied Physics Program, University of Michigan, Ann Arbor, MI, USA. Electronic address:
Hydrogels can serve as local drug delivery depots that protect the biological activity of labile therapeutics. However, drug release from conventional hydrogels is typically rapid, which is not ideal for many therapeutic agents. We developed a composite hydrogel that enables sustained drug release in response to ultrasound.
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