Objective: To observe the survival of hand allograft under the state of immunosuppression and the pathological changes of rejection in the recovery process.
Methods: The biopsies of the skin, nerve, muscle, tendon and bone tissue of hand allografts during different stages from 1 day to 7 months after operation were observed using routine histological technique.
Results: No significant changes due to rejection in skin, nerve, muscle and bone tissue were observed. But different degrees of weak rejective changes were found on the wall of blood vessels; in the muscle and nerve the reactions were markedly stronger than those found in skin tissues.
Conclusions: The rejection in deep tissues should be monitored in controlling the rejection of hand allograft.
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