A Shigella sonnei strain resistant to cefotaxime and aztreonam (but not ceftazidime) was isolated from the stool sample of a 7-y-old outpatient. Double disk synergy test, isoelectric focusing, polymerase chain reaction and sequence analysis confirmed that the isolate produced CTX-M-3, an extended-spectrum beta-lactamase (ESBL). This is the first report from Turkey of Shigella spp. producing an ESBL, and of CTX-M type enzyme.
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http://dx.doi.org/10.1080/00365540310013270 | DOI Listing |
Antibiotics (Basel)
October 2024
Department of Microbiology, National Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.
Microorganisms
August 2024
Department of Medical Microbiology, Medical Faculty, Medical University, 1431 Sofia, Bulgaria.
The aim of the present work was to genetically characterise cefotaxime-resistant enterobacteria isolated from community carriers in Bulgaria. In total, 717 faecal samples from children and adults in five medical centres in Sofia, Pleven and Burgas were examined. Antimicrobial susceptibility was evaluated by the disk diffusion method.
View Article and Find Full Text PDFJAC Antimicrob Resist
October 2024
INRAE, Université de Tours, ISP, Nouzilly, France.
Background: In a previous nationwide survey in the Lebanese broiler production, multidrug-resistant CTX-M-producing were found to carry the mobile colistin resistance gene .
Objectives: To investigate the mobile genetic supports responsible for the spread of these resistance genes among in healthy broilers in Lebanon.
Methods: Thirty-three and - positive of various sequence types from 17 broilers farms were subjected to conjugation assays.
Microorganisms
June 2024
Department of Infection Biology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.
, a member of the commensal intestinal microbiota, is a significant aetiology of urinary tract infections (UTIs) and has a propensity for acquiring multidrug resistance characteristics, such as extended-spectrum beta-lactamases (ESBLs). Despite the increase in the incidence of ESBL-producing infections in sub-Saharan Africa, routine ESBL detection in Ghana is often absent, and molecular data on ESBL genotypes is scarce. Eleven ESBL-producing recovered from mid-stream urine samples were subjected to antimicrobial susceptibility testing and whole-genome sequence analyses.
View Article and Find Full Text PDFSci Rep
May 2024
Department of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Guldhedsgatan 10A, 413 46, Gothenburg, Sweden.
Plasmids encoding bla genes have greatly shaped the evolution of E. coli producing extended-spectrum beta-lactamases (ESBL-E. coli) and adds to the global threat of multiresistant bacteria by promoting horizontal gene transfer (HGT).
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