Background: Pilomatrixoma is a benign tumor of the skin, preferentially found in children. The final diagnosis is made by biopsy. High resolution ultrasound (US) is a non invasive method for its diagnosis.
Aim: To describe the US findings in children with pilomatrixoma.
Material And Methods: Fifty five patients with 62 clinically suspected pilomatrixomas were studied by US. All examinations were done with an ATL HDI 5000, linear 5-12 MHz transducer. Pathological study confirmed the diagnosis pilomatrixoma in 52 cases.
Results: Fifty of 52 pilomatrixomas were diagnosed by US, with a sensitivity of 96%. The mean age of patients was 7.5 years. Forty seven lesions (90%) were located in the head, neck or upper extremities and their mean size was 8.5 mm. Thirty two lesions were hypodermal, 14 were dermohypodermal and 6 were dermal. In 44 lesions the contour was regular and non delineated, 44 lesions were oval, 41 lesions had an acoustic shadow, 36 were echogenic or hyperechogenic, 31 had a peripheral halo (60%), 55 had calcifications (98%), nine had perilesional vessels, 2 had intratumoral vessels and 7 had inflammatory changes. US excluded the diagnosis of pilomatrixoma in 10 lesions formulating a correct differential diagnosis in eight, with a specificity of 80%.
Conclusions: Pilomatrixomas had two US types of presentation. The first is a well defined nodule with peripheral halo partially calcified or with microcalcifications. The second is a completely calcified nodule without peripheral halo and with a strong acoustic shadow. US is a useful, sensitive and specific diagnostic method for pilomatrixoma.
Download full-text PDF |
Source |
---|
Front Neurol
November 2024
Department of Maxillofacial Orthopaedics and Orthodontics, Pomeranian Medical University in Szczecin, Szczecin, Poland.
Background: Orthodontic treatment is frequently correlated with different levels of discomfort and pain, caused by the application of forces to move the teeth. The mechanism of orthodontic pain is based on the initially activation of sensory receptors in periodontal tissues which results in a cascade of nociceptive pain processing and transduction in both the central and peripheral nervous systems that is finally experienced by patients. The perception of pain is subjective and varies among people, as it is influenced by both general and individual elements.
View Article and Find Full Text PDFPulmonary tumoral thrombotic microangiopathy (PTTM) is a rare but fatal complication in patients with cancer that causes death due to sudden respiratory distress, pulmonary hypertension, and right ventricular dysfunction. Early diagnosis and intensive treatment are important for improving patient prognosis. Herein, we describe the clinical and CT findings of 10 patients who were clinically diagnosed with PTTM at our hospital over the past 18 years.
View Article and Find Full Text PDFJ Med Chem
December 2024
Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institutes of Health, Bethesda, Maryland 20892, United States.
Rigidified nucleoside derivatives with (N)-methanocarba replacement of ribose have been repurposed as peripheral subtype-selective 5-HT serotonin receptor antagonists for heart and lung fibrosis and intestinal/vascular conditions. 4'-Cyano derivative (MRS8209; , 4.27 nM) was 47-fold (human binding, but not rat and mouse) and 724-fold (functionally) selective at 5-HTR, compared to antitarget 5-HTR, and predicted to form a stable receptor complex using docking and molecular dynamics.
View Article and Find Full Text PDFAm J Vet Res
December 2024
AniCura Clinica Veterinaria Dell'Orologio, Sasso Marconi, Bologna, Italy.
Objective: The aim of this study was to evaluate the CT features of pulmonary metastases in dogs with hemangiosarcoma (HSA) at various sites. Additionally, the CT characteristics of extrapulmonary metastases in the same population were assessed.
Methods: Retrospective, observational, and descriptive study conducted from April 2013 to January 2024.
Microorganisms
September 2024
Faculty of Science and Engineering, The University of Greenwich at Medway, Central Avenue, Chatham Maritime, Kent ME4 4TB, UK.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!