AI Article Synopsis
- The study investigates how race influences the levels of ABO antibodies by comparing the haemolytic activity in Black and White Zimbabweans.
- It uses a spectrophotometric method to measure haemoglobin release from red blood cells incubated with serum from both racial groups.
- Results indicate that Black subjects have higher haemolytic activity for both anti-A and anti-B antibodies compared to White subjects, with anti-B being more active within each group.
Article Abstract
Race is thought to be one of the factors determining the level of ABO antibodies. The objective of this study was to compare the haemolytic activity of anti-A and anti-B in two racial groups, Black and White Zimbabweans, living under similar conditions. Serum haemolytic activity was assessed by comparing spectrophotometrically, released haemoglobin when known A1 and B red cells were incubated in equal volumes of subjects' serum and water. Serum from Black subjects showed greater haemolytic activity of anti-A and anti-B than serum from White subjects. Within each racial group, anti-B showed greater haemolytic activity than anti-A. Race may be an important factor in the haemolytic activity of ABO antibodies.
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