The case of a 40-year-old male patient come to the emergency service with symptoms suspicious of biliary colic, is presented. Liver sonography was requested to evaluate the parenchyma, the gallbladder and bile duct caliber in the suspicion of lithiasis. During the examination a hyper-reflecting image with posterior shadowing was detected at the level of the gallbladder infundibulum. However, the shadowing was not typical of lithiasis. This aroused some doubts and the scan was repeated after some minutes: an absolutely normal infundibulum was visualized. The shadowing was therefore an artifact probably due to a partial volume effect of the air contained in the distended duodenum, in contact with the gallbladder. The formation process of the sonographic image is carefully analyzed with particular reference to the situations generating artifacts.
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Clin Dermatol
January 2025
Agnes Irwin School. Rosemont, Pennsylvania, USA.
The smile is a complex human facial expression, most commonly associated with joy. We present a detailed view on Leonardo Da Vinci's painting of Saint John the Baptist, between 1516 to 1516, which illustrates a smiling saint, which has evoked multiple explanations and theories. Discussing Da Vinci's concept of painting as science media and the two merely contradictory painting techniques chiaroscuro and sfumato, we attempt to approach this picture.
View Article and Find Full Text PDFJ Dairy Sci
January 2025
Department of Animal Science, Food and Nutrition (DIANA), Faculty of Agricultural, Food and Environmental Sciences, Università Cattolica del Sacro Cuore, 29122 Piacenza, Italy.
The mismatch between the nutrient intake from the diet and the output by the mammary gland causes a negative energy balance in transition dairy cows, that, if excessive, can promote several metabolic disorders. Other relevant phenomena occur during transition, such as inflammation at calving and changes in immunocompetence, redox balance, and mineral metabolism. Despite the efforts, some aspects of the adaptive mechanisms observed in the transition period still need to be clarified.
View Article and Find Full Text PDFCurr Opin HIV AIDS
December 2024
Clinical and Research Unit of Clinical Immunology and Vaccinology, Bambino Gesù Children's Hospital, IRCCS.
Purpose Of Review: This review highlights the role of monocytes in the pathogenesis of HIV-1 infection, focusing on their involvement in the inflammatory response and their function as viral targets and long-term reservoirs.
Recent Findings: Monocytes have been categorized into three subsets: classical, intermediate, and nonclassical, each with distinct functional characteristics. Advances in genetic sequencing technologies have enabled a more in-depth exploration of the phenotypic and functional variations among these subsets, particularly in the context of HIV.
J Biochem Mol Toxicol
January 2025
Department of Ophthalmology, Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
The eye is considered to be an immune-privileged region. However, several parts of the eye have distinct mechanisms for delivering immune cells to the injury sites or even in response to aging. Although these immune responses are intended to be protective, the visual acuity can be compromised by the release of pro-inflammatory cytokines by immune cells, which induce chronic inflammation and fibrosis.
View Article and Find Full Text PDFPhys Rev Lett
December 2024
Dahlem Center for Complex Quantum Systems, Freie Universität Berlin, 14195 Berlin, Germany.
Schemes of classical shadows have been developed to facilitate the readout of digital quantum devices, but similar tools for analog quantum simulators are scarce and experimentally impractical. In this Letter, we provide a measurement scheme for fermionic quantum devices that estimates second and fourth order correlation functions by means of free fermionic, translationally invariant evolutions-or quenches-and measurements in the mode occupation number basis. We precisely characterize what correlation functions can be recovered and equip the estimates with rigorous bounds on sample complexities, a particularly important feature in light of the difficulty of getting good statistics in reasonable experimental platforms, with measurements being slow.
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