Strain-induced regioselectivities in reactions of benzyne possessing a fused four-membered ring.

Org Lett

Department of Chemistry, Tokyo Institute of Technology, and CREST, Japan Science and Technology Corporation (JST), O-okayama, Meguro-ku, Tokyo 152-8551, Japan.

Published: October 2003

[reaction: see text] A fused four-membered ring has a powerful directing ability in effecting the regioselective reactions of benzyne with ketene silyl acetal, nucleophile, and alpha-alkoxyfuran.

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http://dx.doi.org/10.1021/ol034877pDOI Listing

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