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Magnetic Resonance Imaging Findings of Placenta Accreta Spectrum Disorder: A Pictorial Review.
Top Magn Reson Imaging
December 2024
Department of Radiology, La Rabta Hospital of Tunis, University of Medicine of Tunis, Tunis, Tunisia; and.
Magnetic resonance imaging (MRI) is used for diagnosing placenta accreta spectrum disorders (PASDs) because of its advanced soft-tissue contrast and spatial resolution capabilities, offering better contrast, improved spatial resolution, and a wider field of view compared with ultrasound. Using a 1.5-Tesla MRI protocol with multiple sequences, MRI can detect indicative signs of PASD such as placental signal heterogeneity, interruption of the myometrium-placenta interface, and abnormal vascularization.
View Article and Find Full Text PDFEndometrial cancer detected unusually after an ankle fracture secondary to severe anemia in an obese woman with heavy menstrual bleeding: A case report.
Mol Clin Oncol
January 2025
Department of Obstetrics and Gynecology, Pusan National University School of Medicine, Busan 49241, Republic of Korea.
Endometrial cancer (EC) is a growing public health concern in developed countries. The incidence of EC is increasing, particularly in younger women (aged <50 years). Ankle fractures are relatively common orthopedic injuries, with the most common mechanisms being falls or trauma.
View Article and Find Full Text PDFRetrospective study of the factors involved in the development of adenomyosis and the link between adenomyosis and breast cancer.
Med Pharm Rep
October 2024
Faculty of Medicine, Victor Babes University of Medicine and Pharmacy, Timişoara, Romania.
Background And Aims: Adenomyosis is a heterogeneous disease, which differs from patient to patient. The objective of our study was to evaluate the risk factors that influence the occurrence of adenomyosis, more precisely to highlight aspects that may be used in practice. In addition, the impact of levonorgestrel (a possible predisposing factor in the occurrence of adenomyosis) on MDA-MB-231 cells was evaluated, trying to obtain a link between adenomyosis and mammary cancer.
View Article and Find Full Text PDFIntratumoral and peritumoral habitat imaging based on multiparametric MRI to predict cervical stromal invasion in early-stage endometrial carcinoma.
Acad Radiol
October 2024
Department of MRI, the First People's Hospital of Yunnan Province, Kunming, Yunnan 650032, China (X.W., Z.G., H.D., G.B., Q.B); The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan 650500, China (X.W., R.K., Z.G., H.D., G.B., Q.B.). Electronic address:
Article Synopsis
- The study aims to determine how effective multiparametric MRI-based imaging is in predicting cervical stromal invasion in patients with early-stage endometrial carcinoma.
- Researchers analyzed MRI and clinical data from 680 patients, utilizing advanced algorithms to categorize structural and functional habitats in the tumors.
- Results indicated that combining clinical predictors with a specific functional habitat model improved prediction accuracy, suggesting this method is a valuable, noninvasive tool for assessing cervical stromal invasion risk.
Spatially restricted ecto-5'-nucleotidase expression promotes the growth of uterine leiomyomas by modulating Akt activity.
FASEB J
October 2024
Department of Obstetrics & Gynecology, University of South Florida Morsani College of Medicine, Tampa, Florida, USA.
Article Synopsis
- - Uterine leiomyomas, affecting up to 80% of women, cause issues like abnormal bleeding, pelvic pain, and infertility, but their growth mechanisms are not well understood.
- - Research showed that uterine leiomyomas had lower levels of CD73 expression and adenosine compared to healthy myometrium, suggesting a link to tumor growth regulation.
- - Experiments indicated that adding adenosine or certain receptor agonists inhibited the growth of leiomyoma cells by promoting cell death and reducing key protein expressions, proposing new treatment approaches for these tumors.
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