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Sixty years of recurrence prevention in mood disorders.
Psychiatr Pol
April 2024
Uniwersytet Medyczny w Poznaniu.
This year, we observe sixty's anniversary of the article by a British psychiatrist, Geoffrey Hartigan, demonstrating, for the first time, the possibility of preventing of the recurrence of mood disorders by using lithium salts. Herein, a history of prevention of recurrences of mood disorders both worldwide and in Poland will be presented concerning both lithium and other mood-stabilizing drugs. The merit for verifying the prophylactic lithium effect in the 1960-1970s should be given to Danish researchers, Mogens Schou and Poul Baastrup.
View Article and Find Full Text PDFA sixty-year tryst with photosynthesis and related processes: an informal personal perspective.
Photosynth Res
March 2019
Department of Plant Biology, Department of Biochemistry, Center of Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
After briefly describing my early collaborative work at the University of Allahabad, that had laid the foundation of my research life, I present here some of our research on photosynthesis at the University of Illinois at Urbana-Champaign, randomly selected from light absorption to NADP reduction in plants, algae, and cyanobacteria. These include the fact that (i) both the light reactions I and II are powered by light absorbed by chlorophyll (Chl) a of different spectral forms; (ii) light emission (fluorescence, delayed fluorescence, and thermoluminescence) by plants, algae, and cyanobacteria provides detailed information on these reactions and beyond; (iii) primary photochemistry in both the photosystems I (PS I) and II (PS II) occurs within a few picoseconds; and (iv) most importantly, bicarbonate plays a unique role on the electron acceptor side of PS II, specifically at the two-electron gate of PS II. Currently, the ongoing research around the world is, and should be, directed towards making photosynthesis better able to deal with the global issues (such as increasing population, dwindling resources, and rising temperature) particularly through genetic modification.
View Article and Find Full Text PDFThe cost-effectiveness of surgical treatment of medial unicompartmental knee osteoarthritis in younger patients: a computer model-based evaluation.
J Bone Joint Surg Am
May 2015
Orthopedic and Arthritis Center for Outcomes Research (J.F.K., J.N.K., and E.L.), Department of Orthopedic Surgery (J.F.K., T.S.T., J.N.K., and E.L.), Brigham and Women's Hospital, 75 Francis Street, BC-4016, Boston, MA 02115. E-mail address for E. Losina:
Background: Surgical options for the management of medial compartment osteoarthritis of the varus knee include high tibial osteotomy, unicompartmental knee arthroplasty, and total knee arthroplasty. We sought to determine the cost-effectiveness of high tibial osteotomy and unicompartmental knee arthroplasty as alternatives to total knee arthroplasty for patients fifty to sixty years of age.
Methods: We built a probabilistic state-transition computer model with health states defined by pain, postoperative complications, and subsequent surgical procedures.
Sixty-year perspective on coronary artery bypass grafting in women.
J Thorac Cardiovasc Surg
September 2003
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