The present study deals with the ontogeny of the sleep-wakefulness rhythm in 12 children from the 4th to the 15 month of age. The main findings were as follows: 1. The circadian rhythm of wakefulness and sleep is clearly sep up as of 4 months of age and is characterized by 3 main parameters: a long uninterrupted night sleep period which includes the time interval from midnight to 4 a.m. The duration of this period of time is always equal to or higher than 400 min. The periodicity of the last falling asleep before midnight and the periodicity of the first awakening after midnight are equal or very close to 24 hours. Both seem to be mutually adjusted or connected to each other. 2. Some ages are characterized by significant changes in the daily distribution of the number and duration of sleep spans. 3. These changes suggest the existence of several ultradian rhythmicities which prevail successively throughout the development period under study. 4. There are many important differences between girls and boys.
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J Clin Sleep Med
January 2025
Departamento de Enfermedades Respiratorias, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Study Objectives: Actigraphy devices are used in sleep medicine. The Actiwatch 2 (Philips Respironics) was an example of a frequently used device in this field. Nevertheless, the discontinuation of this device has led to an increased necessity for the implementation of other available actigraphy methods capable of providing objective information.
View Article and Find Full Text PDFCommun Biol
December 2024
Department of Physiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, Anhui, China.
Dexmedetomidine (DexM), a highly selective α-adrenoceptor agonist, significantly reduces postoperative adverse effects, including sleep and circadian rhythm disruptions. Vasoactive intestinal peptide neurons in the suprachiasmatic nucleus (SCN) regulate the synchronization of circadian rhythms with the external environment in mammals. We investigate the effects of DexM on sleep and circadian rhythms, as well as the underlying mechanisms.
View Article and Find Full Text PDFBiomedicines
September 2024
School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Daytime dysfunction, including symptoms like sleepiness, poor memory, and reduced responsiveness, is not well researched. It is crucial to develop animal models and study the biological mechanisms involved. We simulated sleep disorders through sleep deprivation, and stressful stimuli were used to establish daytime functional animal models.
View Article and Find Full Text PDFJ Family Med Prim Care
August 2024
Department of Physiology, GIMS, Greater Noida, Uttar Pradesh, India.
Background: Shift work implementation is essential for providing continuous patient care in hospitals. However, working in shifts on a routine basis may disrupt the circadian pattern and alter the sleep-wakefulness cycle in nurses. Stress due to shift work can influence the adaptability of the cardiovascular system, produce psychophysiological strain and deteriorate work performance in female nurses.
View Article and Find Full Text PDFJ Neurosci Res
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Department of Neurophysiology, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bengaluru, India.
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