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Imported Systemic Endemic Mycoses in Spain 1997-2021: An Analysis of a National Hospital Database.
Mycoses
January 2025
Clinical Medicine Department, Miguel Hernández University, Elche, Spain.
Background: Systemic endemic mycoses are systemic fungal infections typically found in tropical and subtropical regions. Their global incidence is rising, including in nonendemic countries, mainly due to migration and international travel. They are a major cause of morbidity and mortality worldwide, especially in immunocompromised patients.
View Article and Find Full Text PDFNavigating the Complexities of Disseminated Histoplasmosis Diagnosis and Management in the Migrant Population: A Case Report.
Cureus
May 2024
Department of Medicine, Harlem Hospital Center, New York City, USA.
Histoplasma capsulatum is a dimorphic fungus that grows in nature as a mold or in culture but converts to a small yeast during cellular invasion. While most histoplasmosis infections are primarily asymptomatic or mildly symptomatic, disseminated histoplasmosis is a relentlessly progressive granulomatous disease that can mimic other granulomatous diseases, such as tuberculosis, sarcoidosis or coccidioidomycosis, more so in the proper context of immunosuppression. The current global migrant crisis, particularly the United States migrant crisis conversation is mostly socio-political; however, it also has a public health implication as exemplified by the case of a 35-year-old male who migrated from Haiti via Chile and Mexico to the United States.
View Article and Find Full Text PDFOverview of invasive fungal infections in children in South America - the threat of resistant Candida species and the role of climate change in the new geographic distribution of endemic systemic mycosis.
Curr Opin Pediatr
April 2024
Department of Pediatrics and Pediatric Infectious Diseases, Escola de Medicina Estácio-Idomed, Ribeirão Preto, São Paulo State, Brazil.
Purpose Of Review: Invasive fungal infection (IFI) in children is a growing problem with crescent morbidity and mortality, well recognized in developed countries, affecting mainly immunocompromised children, including neonates and children in intensive care units. The burden of IFI in South American children is less well comprehended. In addition, the current epidemiology of endemic systemic mycoses in children may have changed over time.
View Article and Find Full Text PDFFungal Lesions of the Oral Mucosa Diagnosis and Management.
Oral Maxillofac Surg Clin North Am
May 2023
Division of Oral and Maxillofacial Pathology, University of Minnesota School of Dentistry, Malcom Moos Health Sciences Tower, 515 Delaware Street, Southeast, Minneapolis, MN 55455, USA.
Oral fungal infections are opportunistic and due to impaired host resistance. The increasing number of immunosuppressed individuals contributes to rising numbers of mycoses worldwide, and the ease of global migration has allowed the geographic range of endemic mycoses to expand. Deep fungal infections can clinically mimic other pathologic conditions including malignancy.
View Article and Find Full Text PDFRe-drawing the Maps for Endemic Mycoses.
Mycopathologia
October 2020
Division of Infectious Diseases, Department of Internal Medicine, University of Kansas, Kansas City, KS, USA.
Endemic mycoses such as histoplasmosis, coccidioidomycosis, blastomycosis, paracoccidioidomycosis, and talaromycosis are well-known causes of focal and systemic disease within specific geographic areas of known endemicity. However, over the past few decades, there have been increasingly frequent reports of infections due to endemic fungi in areas previously thought to be "non-endemic." There are numerous potential reasons for this shift such as increased use of immune suppressive medications, improved diagnostic tests, increased disease recognition, and global factors such as migration, increased travel, and climate change.
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