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Background: Vulvar carcinoma is an uncommon gynecological tumor primarily affecting older women. Its treatment significantly impacts the quality of life and, not least, aesthetics because of the mutilating surgery it requires.

Objectives: The management requires a multidisciplinary team of specialists who know how to care for the patient in her entirety, not neglecting psychological aspects and reconstructive surgery.

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Surgical Management of Gynecologic Cancers.

Hematol Oncol Clin North Am

February 2025

Department of Obstetrics and Gynecology, University of California, 333 City Boulevard West, Suite 1400, Orange, CA 92868, USA.

This article addresses the role of surgery in the management of gynecologic cancers with liver metastases. The authors review the short-term and long-term outcomes of aggressive resection through retrospective and randomized studies. Although the data supporting aggressive resection of liver metastasis are largely retrospective and case based, the randomized control data to address neoadjuvant versus chemotherapy have been widely criticized.

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Article Synopsis
  • The study focuses on the management of advanced ovarian cancer, highlighting the gold standard of complete removal of visible tumors, and exploring the implications of delayed cytoreductive surgery for patients who cannot undergo initial or interval surgery.
  • It is a retrospective analysis of patients with stage IIIC or higher ovarian cancer at the Northern Gynaecological Oncology Centre over six years, comparing survival outcomes between two groups: those who received only chemotherapy and those who had delayed surgery after six cycles.
  • Of the 89 patients evaluated, most completed six cycles of chemotherapy without surgery, while a smaller group underwent delayed surgery, suggesting a potential benefit from this approach in specific cases where initial surgery was not feasible.
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Article Synopsis
  • Krukenberg tumor is a rare type of ovarian cancer that often shows up with symptoms like abdominal pain and swelling, commonly due to both ovaries being affected.
  • The case study discusses a 39-year-old woman who experienced unusual symptoms like abdominal distension and shortness of breath, leading to the discovery of the tumor.
  • The tumor was confirmed to be signet ring cell carcinoma, and it was associated with Pseudo-Meigs' syndrome, highlighting the importance for doctors to consider this syndrome in similar cases for potential effective treatment.
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