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Efficacy and safety of topical sevoflurane in the treatment of chronic skin ulcers.
Am J Health Syst Pharm
May 2017
Pharmacy Department, Hospital of Poniente, El Ejido, Spain.
Purpose: Results of efficacy and safety assessments of topical sevoflurane use in patients with long-term treatment-refractory vascular ulcers are reported.
Methods: Patients were randomly assigned to receive sevoflurane instillations (1 mL per cm of ulcer area 1-4 times daily) plus standard wound care (ulcer cleaning, debridement, and dressing changes) or standard care only. Topical sevoflurane was initiated during hospitalization, with self- or nurse-administered instillations continued after discharge.
An equivalence study comparing nitrous oxide and oxygen with low-dose sevoflurane and oxygen as inhalation sedation agents in dentistry for adults.
Br Dent J
November 2014
Sedation and Special Care Dentistry, School of Dentistry, College of Biomedical and Life Sciences, Cardiff University, Heath Park, Cardiff, CF14 4XY.
Objective: The aim of this study was to examine whether sevoflurane in oxygen was equivalent to near equipotent concentrations of nitrous oxide in oxygen when used as an inhalation sedation agent in terms of patient and user acceptability.
Method: Forty anxious dental patients referred to the sedation suite at Cardiff University School of Dentistry received either nitrous oxide to a maximum concentration of 40% or sevoflurane to a maximum concentration of 0.3% for a routine maxillary plastic restoration with articaine infiltration local analgesia.
Clonidine premedication effects on inhaled induction with sevoflurane in adults: a prospective, double-blind, randomized study.
Acta Anaesthesiol Scand
February 2006
Department of Anesthesiology and Critical Care Medicine, Tottori University Faculty of Medicine, Yonago, Tottori, Japan.
Background: The purpose of this study was to evaluate whether oral clonidine premedication becomes an alternative to N2O in terms of shortening the induction time and attenuation of the adrenergic response to tracheal intubation during inhalation induction with sevoflurane, and to evaluate the quality of anesthetic induction according to the patient's satisfaction.
Methods: We studied 84 female patients who were randomly allocated into four study groups: Groups I and II received a placebo orally, and Groups III and IV received clonidine at 150 and 300 microg, respectively, 90 min before induction of anaesthesia. Patients were anesthetized using a triple-deep-breath technique with 5% sevoflurane in Groups I, III and IV, and with 60% N2O-5% sevoflurane in group II.
Anesthetic requirement is increased in redheads.
Anesthesiology
August 2004
Outcomes Research Institute, University of Louisville, Louisville, Kentucky. USA
Article Synopsis
- - The study investigated whether red-haired women require more inhalational anesthetic (desflurane) than dark-haired women due to specific genetic mutations associated with red hair.
- - Researchers tested 20 healthy women (10 redheads and 10 dark-haired) and found that redheads needed a significantly higher concentration of desflurane to achieve the same level of anesthesia as dark-haired women.
- - The results suggest that the need for anesthetics in red-haired individuals may be linked to their unique genetic variations in the melanocortin-1 receptor.
[Perioperative management of a neonate with aglossia-adactylia syndrome].
Masui
July 2001
Department of Anesthesiology, Osaka Medical Center and Research Institute for Maternal and Child Health, Izumi 594-1101.
Aglossia-adactylia syndrome is a rare disorder characterized by aglossia and deformity of the limbs of variable degree. We managed a 2-day-old neonate with ileojejunal atresia with aglossia-adactylia syndrome. He was scheduled for the repair of the intestinal atresia, gastrostomy and palatal impression taking, under general anesthesia with sevoflurane supplemented with fentanyl.
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