This paper presents an analysis of trends in mortality from malignant melanoma of the skin in The Netherlands, 1950-1988. Statistical analyses show that time period effects are needed to describe the mortality trends in The Netherlands. Because this contrasts with reports from other countries, in which the trends were ascribed to a cohort effect only, log-linear models including the three factors age, time period and birth cohort, were fitted to the data. To be able to separate time period effects from birth cohort effects we assumed a mathematical function for the mortality rates in relation to age. The results obtained in this way indicate that time period effects increased up to 1970. An increase of birth cohort effects is seen for cohorts born between 1900 and 1955. For cohorts born after 1955 the mortality from melanoma seems to decrease. The most plausible explanation for the time period effect probably is improvement in death certification.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0959-8049(93)90585-4 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Increasing Access to Mental Health Supports for 18- to 25-Year-Old Indigenous Youth With the JoyPop Mobile Mental Health App: Study Protocol for a Randomized Controlled Trial.
JMIR Res Protoc
January 2025
Department of Psychology, Lakehead University, Thunder Bay, ON, Canada.
Background: Transitional-aged youth have a high burden of mental health difficulties in Canada, with Indigenous youth, in particular, experiencing additional circumstances that challenge their well-being. Mobile health (mHealth) approaches hold promise for supporting individuals in areas with less access to services such as Northern Ontario.
Objective: The primary objective of this study is to evaluate the effectiveness of the JoyPop app in increasing emotion regulation skills for Indigenous transitional-aged youth (aged 18-25 years) on a waitlist for mental health services when compared with usual practice (UP).
Long-Term Treatment With Ocrelizumab in Patients With Early-Stage Relapsing MS: Nine-Year Data From the OPERA Studies Open-Label Extension.
Neurology
February 2025
Department of Neurology and Center of Clinical Neuroscience, First Medical Faculty, General University Hospital and Charles University, Prague, Czech Republic.
Background And Objectives: Patients with multiple sclerosis (MS) may demonstrate better disease control when treatment is initiated on high-efficacy disease-modifying therapies (DMTs) from onset. This subgroup analysis assessed the long-term efficacy and safety profile of the high-efficacy DMT ocrelizumab (OCR) as first-line therapy for early-stage relapsing MS (RMS).
Methods: Post hoc exploratory analyses of efficacy and safety were performed in a subgroup of treatment-naive patients with RMS who received ≥1 dose of OCR in the multicenter OPERA I/II (NCT01247324/NCT01412333) studies.
The time course and organization of hippocampal replay.
Science
January 2025
Department of Neuroscience, University of California, Berkeley, Berkeley, CA, USA.
The mechanisms by which the brain replays neural activity sequences remain unknown. Recording from large ensembles of hippocampal place cells in freely behaving rats, we observed that replay content is strictly organized over multiple timescales and governed by self-avoidance. After movement cessation, replays avoided the animal's previous path for 3 seconds.
View Article and Find Full Text PDFEvolution of the Danube River's islands on the Bulgaria-Romania border over the last century.
PLoS One
January 2025
Faculty of Geography, University of Bucharest, Bucharest, Romania.
The border line between Bulgaria and Romania was established a century ago on the Danube River's thalweg, going around islands. Over time, islands migrated; to avoid conflicts, islands located on the border line are declared neutral territory by both countries and they exit from use. In this context, the paper aims to draw conclusions on the spatial dynamics of the Danube River's sandy islands along the Bulgaria-Romania border.
View Article and Find Full Text PDFStudy on the cooling effect of the parallel perforated ventilation subgrade in permafrost regions based on the numerical model.
PLoS One
January 2025
Tianjin Key Laboratory of Soft Soil Characteristics and Engineering Environment, Tianjin Chengjian University, Tianjin, China.
The runway in permafrost regions has remarkable temperature sensitivity. Therefore, this paper puts forward to the parallel perforated ventilation subgrade. The reliability and validity of the finite element model of the runway with the parallel perforated ventilation subgrade are verified by comparing with the previous studies.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!