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Testicular cancer in two brothers of a quadruplet: a case report and a review of literature.
Acta Med Litu
January 2017
Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Testicular cancer and a multiple birth are both rare events, and the risk of testicular cancer is increased in twins. In Lithuania, only five quadruplets have been recorded since the middle of the 20th century. In this report, we present two rare events in one family: testicular cancer in two brothers of a quadruplet (three brothers and a sister).
View Article and Find Full Text PDFAndrogen insensitivity syndrome (or Morris syndrome) and other associated pathologies.
Eur Rev Med Pharmacol Sci
November 2010
Unit of Cytogenetic and Molecular Genetics, Madonna delle Grazie Hospital, Matera, Italy.
Background: The androgen insensitivity syndrome (AIS) is a disease connected with the inactivation of AR due to a mutation that inactivate male sexual differentiation, and causes a spectrum of phenotypic anomalies having as a common aspect the loss of reproductive characteristics.
Patients: In this paper the clinical, endocrinological and molecular features of three patients are reported. The first case concerns a 17 years old patient, the second an infant suffering from inguinal hernia that has been surgically corrected when he was 3 months old and finally the third case concerns a 57 years old woman.
"Salvage" surgery for primary mediastinal malignancies: is it worthwhile?
J Thorac Oncol
January 2008
Department of Thoracic Surgery, European Institute of Oncology, Milan, Italy.
Introduction: Indications and results of salvage surgery in mediastinal tumors are still unclear. This study analyzes a single-center experience to assess its mortality, morbidity, and long-term results.
Methods: Mediastinal salvage surgery (MSS) was defined as surgical resection of persistent or recurrent primary mediastinal tumors after previous local treatments with curative intent or exclusive chemotherapy in case of bulky tumors.
Ultrasonic examinations of 3000 pregnant women revealed congenital developmental defects in 22 (0.7%) fetuses: in 4 cases tumors of various sites were detected and in 2 cases the tumors were found in one of the twins. Pathologic and histologic examinations carried out after delivery revealed a sacrococcygeal teratoma and a retroperitoneal dermoid cyst in one fetus, a ganglioneuroma of the retroperitoneal space, located between the bladder and rectum, an intrapericardial teratoblastoma, and a cystic cervical lymphangioma.
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