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Infective endocarditis causing acute aortic occlusion in a patient with systemic lupus erythematosus: A rare case report.
Int J Surg Case Rep
January 2025
Department of Vascular Surgery, Royal Perth Hospital, Perth 6000, Australia; University of Western Australia, School of Surgery, Perth 6000, Australia. Electronic address:
Introduction: We present a unique case of acute aortic occlusion secondary to infective endocarditis (IE).
Presentation Of Case: An Aboriginal Australian woman with systemic lupus erythematosus presented with fever, confusion, tachycardia, and tachypnoea and had cold, pulseless, insensate, and paralysed lower limbs. Computed tomography angiography revealed multifocal occlusion of the distal aorta and lower limb vessels.
Empiric antibiotic therapy resistance and mortality in emergency department patients with bloodstream infection: a retrospective cohort study.
BMC Emerg Med
January 2025
Department of Emergency Medicine, Semmelweis University, Ulloi ut 78/A, Budapest, 1082, Hungary.
Background: Timely management of sepsis in the emergency department, including the use of appropriate antimicrobials, is crucial for improving patient outcomes. Inadequate empiric antimicrobial treatment is associated with potential changes in patient outcomes. We aimed to pinpoint risk factors, characterize antibiotic resistance trends, and investigate the association between antibiotic resistance and mortality among patients with bacteremia admitted to the emergency department.
View Article and Find Full Text PDFProbiotic biofilm modified scaffolds for facilitating osteomyelitis treatment through sustained release of bacteriophage and regulated macrophage polarization.
Mater Today Bio
February 2025
Department of Orthopedic Trauma and Microsurgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, Hubei, China.
Osteomyelitis has gradually become a catastrophic complication in orthopedic surgery due to the formation of bacterial biofilms on the implant surface and surrounding tissue. The therapeutic challenges of antibiotic resistance and poor postoperative osseointegration provide inspiration for the development of bioactive implants. We have strategically designed bioceramic scaffolds modified with (LR) and bacteriophages (phages) to achieve both antibacterial and osteogenic effects.
View Article and Find Full Text PDFEffect of external infusion connection devices replacement frequency on catheter related bloodstream infection.
Sci Rep
January 2025
Nursing Department, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Timely and effective rescue of critically ill children no longer solely relies on advanced medical technology; vascular access plays a pivotal role. Best practice recommendations for nursing in vascular access are critical for ICU patients. However, clear guidelines for the maintenance of external infusion connection devices remain lacking.
View Article and Find Full Text PDFA multimodal approach to reduce the incidence of peripheral venous cannula bacteraemias and improve patient safety.
Br J Nurs
January 2025
Audit and Surveillance Specialist Nurse, Infection Prevention and Control, Royal Devon University Healthcare NHS Foundation Trust.
Background: Incidence of peripheral venous cannula (PVC) bacteraemia have been rising in a trust in the south-west of England, with a 267% increase noted over the 2022/23 financial year compared with the previous year.
Aim: To use a multimodal approach to reduce the incidence of PVC bacteraemia and improve patient safety.
Methods: The initiative consisted of an educational poster highlighting the severity of infection associated with PVCs alongside key prevention messages rooted in Trust policy.
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