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Clinical, Microbiological Profile, and Treatment Outcomes of Carbapenem-Resistant Urinary Tract Infections in a Tertiary Care Hospital.
Indian J Nephrol
July 2024
Department of Nephrology, M S Ramaiah Medical College, Bangalore, India.
Background: Carbapenem-resistant urinary tract infections (CR-UTIs) are a major global health threat. Many factors contribute to the increasing incidence of CR-UTI. Owing to the limited availability of treatment options, CR-UTIs are highly challenging to treat.
View Article and Find Full Text PDFRaw Ocimum sanctum L. leaf extract modulates the pharmacokinetic of ceftriaxone and increases its bioavailability in staphylococcal mastitis.
Indian J Pharmacol
September 2024
Department of Pharmacology and Toxicology, West Bengal University of Animal and Fishery Sciences, Kolkata, West Bengal, India.
Background: To study the pharmacokinetic interaction of cephalosporin antibiotic ceftriaxone (CFT) with raw undiluted Ocimum sanctum L. leaf juice in chronic staphylococcal mastitis in caprine.
Materials And Methods: Chronic inflammation of the udder was evoked in goats by Staphylococcus aureus (J638) intracisternal inoculation 2000 cfu for 30 days into the left udder.
High-effective, convenient and environmental-friendly MOFs-chitosan-glyoxal composite film for ceftizoxime adsorption: Behavior and mechanisms.
Int J Biol Macromol
December 2024
School of Ecological and Environmental Sciences, Shanghai Engineering Research Center of Biotransformation of Organic Solid Waste, Shanghai Key Lab for Urban Ecological Processes and Eco-Restoration, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China; Institute of Eco-Chongming (IEC), 3663 North Zhongshan Road, Shanghai 20062, China. Electronic address:
Article Synopsis
- A new composite film called PCN@CSG was created by integrating PCN-222 into a chitosan substrate, proving effective for adsorbing the antibiotic ceftizoxime.
- * The film shows strong adsorption capabilities and structural integrity in tough conditions, achieving a high adsorption capacity of 561.7 mg/g and maintaining over 90% removal efficiency after multiple reuse cycles.
- * The adsorption process follows specific kinetic and isotherm models, indicating it's primarily controlled by chemisorption, making the PCN@CSG a promising eco-friendly option for removing cephalosporins from water.
Impact of ciprofloxacin with autophagy on renal tubular injury.
Medicine (Baltimore)
October 2024
Department of Biochemistry, School of Medicine, Catholic University of Daegu, Daegu, Republic of Korea.
Backgrounds: Renal tubular injury caused by oxidative stress and inflammation results in acute kidney injury. Recent research reported that antibiotics may protect renal tubules from progressive deterioration, but the underlying mechanism remains unclear. Therefore, we investigated the efficacy and mechanism of action of antibiotics against renal tubular injury.
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