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Clinical characteristics, treatment, and outcomes of nivolumab-induced uveitis.
Immunopharmacol Immunotoxicol
January 2025
College of Pharmacy, Changsha Medical University, Changsha, Hunan, 410219, China.
Nivolumab has been linked to occurrences of uveitis, yet the clinical features associated with these episodes remain unclear. This study aimed to explore the clinical characteristics of uveitis induced by nivolumab and to offer guidance for its prevention, diagnosis, and treatment. We conducted a retrospective analysis by gathering case reports related to nivolumab-induced uveitis from both Chinese and English databases, covering the period from inception until September 30, 2024.
View Article and Find Full Text PDFBiofabrication of zinc oxide nanoparticles using Moringa oleifera, characterization and statistical optimization for their application in crystal violet adsorption.
Sci Rep
January 2025
Department of Biology, College of Sciences and Arts Khulais, University of Jeddah, 21959, Jeddah, Saudi Arabia.
Crystal violet (Cry) is an essential textile dye belonging to the triphenylmethane group, that is widely used in the textile industry. It is also applied for paper printing and Gram staining. Previously, it was significant as a topical antiseptic due to its antibacterial, antifungal, and anthelmintic properties.
View Article and Find Full Text PDFSp3 ameliorated experimental autoimmune encephalomyelitis by triggering Socs3 in Th17 cells.
J Adv Res
January 2025
Department of Biotechnology, School of Life Sciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou 510006, China; Guangdong Provincial Key Laboratory of Advanced Drug Delivery, Guangdong Provincial Engineering Center of Topical Precise Drug Delivery System, Guangdong Pharmaceutical University, Guangzhou 510006, China. Electronic address:
Introduction: Although it is believed that chronic inflammatory and degenerative diseases of the central nervous system are mediated by autoimmune Th17 cells, the underlying mechanisms remain largely unexplored. Recent studies and our research have revealed that Sp3 was blocked in multiple sclerosis (MS) patients and experimental autoimmune encephalomyelitis (EAE). However, it remained unclear why it is silent and how it regulates Th17 cell differentiation in MS.
View Article and Find Full Text PDFEnhancement of burn wound healing using optimized bioactive probiotic-loaded alginate films.
Int J Biol Macromol
January 2025
Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 1414614411, Iran. Electronic address:
Wound infection can prolong the healing process, leading to various complications. Although the use of antibiotics is common, it presents challenges such as poor pharmacokinetics. The prevalence of antibiotic resistance has further complicated wound management.
View Article and Find Full Text PDFCorneal Perforation Associated with Pembrolizumab - A Case Report with Literature Review.
Ocul Immunol Inflamm
January 2025
Universiti Malaya Eye Research Centre (UMERC), Department of Ophthalmology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Purpose: To shed light on one of the ocular adverse effects related to pembrolizumab.
Method: Case report and literature review.
Result: A 53-year-old gentleman with underlying Stage III B renal cell carcinoma with lung metastasis and gout presented in June 2021 with bilateral red eyes following Coronavirus disease (COVID-19) vaccination.
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