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Effects of Dichloromethane, Nitrate, and Sulfhemoglobin-Induced Substances on Carboxyhemoglobin Detection: A Comprehensive Review.
J Anal Toxicol
December 2024
Shanghai Key Laboratory of Crime Scene Evidence, Shanghai Institute of Forensic Sciences, Shanghai, PR China.
Carbon monoxide (CO) is a common gaseous toxin that causes severe poisoning symptoms. Accurate detection of the formation of carboxyhemoglobin (COHb) in the blood is very important for the identification of CO poisoning. In this review, the effects of exogenous toxins, including dichloromethane (DCM), nitrite and hydrogen sulfide, on the determination of COHb by spectrophotometry were summarized by comparing epidemiological data, case studies and analytical methods.
View Article and Find Full Text PDFEffect of watering before slaughter and the evisceration method on the quality characteristics of fattened goose liver.
Poult Sci
December 2024
Hungarian University of Agriculture and Life Sciences, Buda Campus, Institute of Food Science and Technology, Department of Livestock Product and Food Preservation Technology, Hungary.
The aim of this study was to investigate the effect of watering before slaughter and different evisceration methods on the quality characteristics of fattened goose liver. A total of randomly selected 60 male Greylag Landaise geese (Anser anser) were used to execute the experiment which had been force-fed during their growing period. In the slaughterhouse, randomized block design was followed and the birds were randomly divided into four experimental groups and half of the them (30 birds) were given 200 ml tap water.
View Article and Find Full Text PDFSulfhemoglobinemia in a 53-Year-Old With a History of Phenazopyridine Misuse.
Cureus
June 2023
Department of Pulmonary and Critical Care Medicine, Brooke Army Medical Center, San Antonio, USA.
Sulfhemoglobin is formed by the irreversible bonding of sulfur atoms to the heme molecule. Oxygen is then unable to bind the heme molecule, rendering the hemoglobin molecule unable to carry oxygen. The most common etiology of sulfhemoglobinemia is the use/misuse of sulfur-containing medications such as AZO.
View Article and Find Full Text PDF[Sulfhemoglobinemia secondary to the use of zopiclone. Report of two cases].
Rev Med Chil
October 2022
Sección de Hematología, Servicio de Medicina, Hospital del Salvador, Santiago, Chile.
Article Synopsis
- Sulfhemoglobin (SulfHb) is a compound formed when hemoglobin is oxidized by sulfur compounds, often linked to drug use or bacterial overgrowth in the intestines, and presents as cyanosis with normal oxygen levels in the blood.
- A case study reported two women with cyanosis after high doses of zopiclone, where typical diagnoses like methemoglobinemia were ruled out, complicating the confirmation of sulfhemoglobinemia due to interference with co-oximetry tests.
- Although sulfhemoglobinemia is usually self-limiting and confirmatory tests are scarce in Chile, it is crucial to distinguish it from methemoglobinemia to prevent unnecessary treatments.
A Suggested Mechanism for Green Discoloration of the Postmortem Brain.
Am J Forensic Med Pathol
June 2023
From the Section of Legal Medicine, Department of Social Medicine, Faculty of Medicine, University of Miyazaki.
In the putrefied brain, the cortex and basal ganglia show dark-grayish to green discoloration due to sulfhemoglobin formed from hydrogen sulfide (H 2 S) produced by endogenous bacteria and hemoglobin. In this study, we propose and demonstrate another mechanism of green discoloration in the brain. The formalin-fixed brain of a cadaver donated for medical education with no putrefaction was used.
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