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Lingo1 in the hippocampus contributes to cognitive dysfunction after anesthesia and surgery in aged mice.
Int J Biol Sci
January 2025
Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Cognitive impairment caused by anesthesia and surgery is one of the most common complications with multiple etiologies that occurs in elderly patients. The underlying mechanisms are not fully understood, and there is a lack of therapeutic strategies. Increasing evidence has demonstrated that myelin loss, abnormal phosphorylation of the tau protein and neuronal apoptosis are substantial driving factors of cognitive deficits.
View Article and Find Full Text PDFComparative study between using a stapler and hand sewing in bullectomy.
Kardiochir Torakochirurgia Pol
December 2024
Department of Cardiothoracic Surgery, Assiut University Hospital, Faculty of Medicine, Assiut University, Assiut, Egypt.
Introduction: Spontaneous pneumothorax is a life-threatening thoracic condition that could be either primary spontaneous pneumothorax (PSP) in the absence of an underlying lung disease or secondary spontaneous pneumothorax (SSP) in the presence of an underlying lung disease. In the case of recurrent, contralateral spontaneous pneumothorax or persistent air leak with a chest drain, surgery with bullectomy associated with pleurectomy or pleurodesis is the gold standard management.
Aim: To compare two different techniques for bullectomy, either by using staplers or by hand sewing.
Application of negative pressure wound therapy to partially closed median sternotomy in a dog.
Can Vet J
January 2025
Veterinary Clinical Sciences Department, College of Veterinary Medicine, University of Minnesota, 1352 Boyd Avenue, St. Paul, Minnesota 55108, USA.
A 6-year-old Labrador retriever dog with a history of pneumonia was presented because of an acute onset of dull mentation and coughing. Diagnostic imaging and cytology revealed a pneumothorax, pneumomediastinum, and pleural effusion, consistent with pyothorax. The dog underwent exploratory sternotomy for lung lobectomy of the right cranial and middle lung lobes.
View Article and Find Full Text PDFTraumatic Hemothorax With Rib Fixation in a Professional Jockey Following a Horse Stomping Incident.
Cureus
December 2024
Faculty of Medicine, Universidad de Guadalajara, Guadalajara, MEX.
Traumatic hemothorax is a serious condition requiring immediate intervention. We present a case of a 48-year-old male professional jockey who suffered traumatic hemothorax, bilateral pulmonary contusions, and multiple rib fractures after being stomped by a horse. Management included intercostal drainage placement, costal fixation from the 5th to the 10th rib, and intensive care unit admission.
View Article and Find Full Text PDFRandomized study of temporary diaphragm pacing for enhanced recovery after surgery in cardiac surgery patients at risk of prolonged mechanical ventilation.
JTCVS Open
December 2024
Division of Cardiac Surgery, University Hospitals Cleveland Medical Center, Cleveland, Ohio.
Objective: Prolonged mechanical ventilation after cardiac surgery significantly increases morbidity and mortality. The aim of this study is to establish the role of diaphragmatic pacing to decrease mechanical ventilation burden in high-risk patients undergoing cardiac surgery.
Methods: This is a prospective, randomized trial of temporary diaphragmatic pacing electrode use in patients undergoing cardiac surgery (NCT04899856).
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