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Post-lactation mass recovery and metabolic hormone dynamics in adult female Weddell seals.
Gen Comp Endocrinol
March 2025
Department of Biological Sciences, Texas Tech University, Box 43131, Lubbock, TX 79409, USA. Electronic address:
Weddell seal (Leptonychotes weddellii) females lose substantial body mass across an intensive, nutritionally restricted lactation period and then must rapidly recover mass during the short Antarctic summer. In this study, we examined endocrine dynamics associated with mass loss across lactation and subsequent realimentation in Weddell seals, comparing patterns between seals that recently gave birth and demographically similar non-reproductive females (skip females) in McMurdo Sound, Antarctica. Postpartum seals near weaning (∼35 days postpartum, n = 64) and skip females (n = 32) were handled during early austral summer (November/December) and rehandled in late summer (January/February).
View Article and Find Full Text PDFHormonal and metabolic responses across phases of combined oral contraceptive use and menstrual cycle in young elite female athletes.
Eur J Appl Physiol
March 2025
CIAMS, Université d'Orléans, Pôle STAPS, Orléans, France.
Purpose: Despite the significant number of female athletes using combined oral contraceptives (COCs), there is scant literature on their hormonal and metabolic effects across different phases.
Methods: In order to contribute to a wider knowledge of COC-action mechanisms involved in athletes' performance and health, we therefore examined the effects of low-dose monophasic COC (ethinylestradiol/levonorgestrel) intake on sex hormones (estradiol, progesterone, sex hormone binding protein (SHBG)) as well as on a large number of pituitary (LH, TSH, prolactin) and peripheral (triiodothyronine, cortisol, DHEA, DHEA-S, aldosterone, osteocalcin, 25(OH)D) basal hormone levels in nine young elite female athletes, across COC administration (first and second half of active hormone intake, washout phases), compared to eleven female athletes without hormonal contraception across their normal menstrual cycle (NMC, i.e.
Influence of genotype and environment on piglet vitality and metabolic state during the suckling period of divergent birth weight classes.
Animal
February 2025
Research Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany; Chair of Animal Breeding and Genetics, Faculty of Agricultural and Environmental Sciences, University Rostock, Justus-von-Liebig-Weg 7, 18059 Rostock, Germany. Electronic address:
The high mortality rate of suckling piglets in commercial farms is a cause for concern and requires the adoption of innovative breeding and management approaches for effective mitigation. Piglets are particularly vulnerable during the first days of life, which concerns especially neonates with a low birth weight. In this study, neonatal adaptation was analysed regarding genotype and housing conditions following hormonally induced farrowing.
View Article and Find Full Text PDFPolygala crotalarioides attenuates erectile dysfunction through improving Rho/ROCK signaling pathway mediated thyroid and gonadal function in kidney Yang deficiency ED rat.
Tissue Cell
June 2025
Yunnan Provincial Hospital of Traditional Chinese Medicine, Yunnan, China. Electronic address:
This study aimed to explore effectiveness and related mechanisms of Polygala crotalarioides in treating erectile dysfunction (ED). Hydrocortisone was used to establish a kidney-Yang deficiency ED rat model. Levels of triiodothyronine(T3), thyroxine(T4), testosterone(T), estradiol(E2) and expressions of RhoA, ROCK1, ROCK2 were determined.
View Article and Find Full Text PDFThiamethoxam at environmentally relevant concentrations induces neurotoxicity in zebrafish larvae through binding with multiple receptors.
Eco Environ Health
March 2025
State Key Laboratory of Pollution Control and Resource Reuse, School of Environment, Nanjing University, Nanjing 210023, China.
Thiamethoxam (THM) is one of the most widely used insecticides globally, which was designed to selectively target nicotinic acetylcholine receptors (nAChRs) in the insect nervous system and is generally considered safe for non-targeted organisms. However, increasing evidence has demonstrated its neurotoxicity in aquatic organisms, though the underlying mechanisms, especially at environmentally relevant concentrations, remain largely unclear. In this study, the swimming distance of zebrafish was significantly shortened by 14.
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