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Osteoarthritis Cartilage
September 2024
Brigham and Women's Hospital, Boston, MA, USA. Electronic address:
Objective: Understanding gender-specific differences in patterns of cartilage loss can improve our knowledge of the pathogenesis of knee osteoarthritis (KOA) development and progression and may inform clinical trials of treatments for KOA. The goal of our observational study was to examine gender differences in patterns of cartilage loss in the central weight-bearing regions of the femur.
Methods: We measured cartilage volume change in the indexed knee of 700 subjects with Kellgren-Lawrence 1, 2, or 3 from the Osteoarthritis Initiative for four follow-up periods (baseline [BL] to 24 mo, BL to 48 mo, BL to 72 mo, and BL to 96 mo) using the local area cartilage segmentation (LACS) method.
Ann Am Thorac Soc
August 2022
Division of Radiology, Lahey Hospital & Medical Center, Burlington, Massachusetts.
Future optimization of computed tomography (CT) lung cancer screening (CTLS) algorithms will depend on clinical outcomes data. To report the outcomes of positive and suspicious findings in a clinical CTLS program. We retrospectively reviewed results for patients from our institution undergoing lung cancer screening from January 2012 through December 2018, with follow-up through December 2019.
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August 1992
Department of Medicine, University of Chicago.
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