A report is given on experiments of rejuvenation which were carried out in the first decenniums of the 20th century. The knowledge of the effect of sexual hormones on the one hand and still missing possibilities of synthesisation on the other gave rise to spectacular transplantations and further operation techniques as well as physical forms of therapy on testicles and ovaries. The fundaments of the scientific theory and the social backgrounds of these side branches of gerontology which established itself only at the end of the thirties are mentioned.
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