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Red Currant ( L.) Fruit Waste Extract and Juice as Potential Spasmolytic Agents.
Plants (Basel)
January 2025
Department of Pharmacy, Faculty of Medicine, University of Niš, Dr. Zoran Djindjić Ave 81, 18000 Niš, Serbia.
Red currant ( L.) berries are rich in bioactive compounds and exhibit nutritive and protective features. This research examined the content of secondary metabolites of the red currant variety Redpoll lyophilized juice and waste extract and their antioxidative and spasmolytic effects.
View Article and Find Full Text PDFThe Potential of SHAP and Machine Learning for Personalized Explanations of Influencing Factors in Myopic Treatment for Children.
Medicina (Kaunas)
December 2024
Graduate Institute of Business Administration, Fu Jen Catholic University, New Taipei City 242, Taiwan.
The rising prevalence of myopia is a significant global health concern. Atropine eye drops are commonly used to slow myopia progression in children, but their long-term use raises concern about intraocular pressure (IOP). This study uses SHapley Additive exPlanations (SHAP) to improve the interpretability of machine learning (ML) model predicting end IOP, offering clinicians explainable insights for personalized patient management.
View Article and Find Full Text PDFChanges in doxylamine-pyridoxine dispensation in Ontario following media attention: Time-series analysis.
Can Fam Physician
January 2025
Assistant Professor in the Leslie Dan Faculty of Pharmacy at the University of Toronto, Scientist at Women's College Hospital Institute for Health System Solutions and Virtual Care in Toronto, Investigator with the Ontario Drug Policy Research Network, and Adjunct Scientist at ICES.
Objective: To understand the possible association between media coverage and changes in the dispensation of doxylamine-pyridoxine in Canada.
Design: Cross-sectional time-series analysis using data from the IQVIA CompuScript database.
Setting: Ten Canadian provinces.
Regular versus as-needed treatments for mild asthma in children, adolescents, and adults: a systematic review and network meta-analysis.
BMC Med
January 2025
Department of Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.
Background: Inhaled corticosteroids (ICS) are recommended treatment for mild asthma. We aimed to update the evidence on the efficacy and safety of ICS-containing regimens, leukotriene receptor antagonists (LTRA), and tiotropium relative to as-needed (AN) short-acting β2-agonists (SABA) in children (aged 6-11 years) and adolescents/adults.
Methods: A systematic review of randomized controlled trials (RCTs) of regular and AN treatment for mild asthma was conducted (CRD42022352384).
Heterotaxy syndrome, dextrocardia, ureteropelvic obstruction, endometriosis, and pulmonary hypertension in an adult with congenital heart defects: a case report.
J Med Case Rep
January 2025
Faculty of Medicine, Damascus University, Damascus, Syria.
Background: Heterotaxia is characterized by an abnormal positioning of the thoracic and/or abdominal organs, resulting in various physiological and hemodynamic implications. Congenital heart disease involves structural irregularities in the heart or major vessels within the chest, leading to functional challenges.
Case Presentation: We present a 26-year-old Arab female patient with a complex medical history involving heterotaxy, dextrocardia, congenital heart disease, and ureteropelvic junction obstruction diagnosed in her first year of life, followed by the identification of endometriosis in her early twenties.
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