A rare case of snake bite poisoning presenting as disseminated intravascular coagulation is presented. It is important to consider this entity in the differential diagnosis of children presenting with acute bleeding disorders in the West Indian islands where Bothrops atrox is present, namely, in Trinidad, St. Lucia and Martinique.
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ACS Omega
December 2024
Avenida Antônio Carlos 6627, Dept. De Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Minas Gerais, Brazil.
species are the main cause of snake bites in rural communities of tropical developing countries of Central and South America. Envenomation by snakes is characterized by prominent local inflammation, hemorrhage and necrosis as well as systemic hemostatic disturbances. These pathological effects are mainly caused by the major toxins of the viperidae venoms, the snake venom metalloproteinases (SVMPs).
View Article and Find Full Text PDFPLoS Negl Trop Dis
December 2024
Programa de Pós-Graduação em Medicina Tropical, Universidade do Estado do Amazonas (UEA), Manaus, Brazil.
Toxicon
November 2024
Laboratorio de Toxinopatología, Departamento de Patología, Facultad de Medicina, José E. Uriburu 950, 5(to) piso (1114), Universidad de Buenos Aires, Buenos Aires, Argentina; Instituto Nacional de Producción de Biológicos I.N.P.B. - A.N.L.I.S. ''Dr. Carlos G. Malbrán'', Ministerio de Salud, Av. Vélez Sarsfield 563 (1282), Buenos Aires, Argentina; Área Investigación y Desarrollo - Venenos, Aracnario-Serpentario. Instituto Nacional de Producción de Biológicos, A.N.L.I.S. "Dr. Carlos G. Malbrán", Av. Velez Sarsfield 563 (1282). Buenos Aires, Argentina. Electronic address:
In this work, we describe an easy, simple, and cost-effective method to assess the proteolytic activity of snake venoms. The method is based on measuring the hydrolytic halo formed by gelatin radial hydrolysis following the incubation of venoms on a solid gelatin-agarose plate. Venoms from Bothrops (B.
View Article and Find Full Text PDFActa Trop
December 2024
Laboratório de Imunologia Celular Aplicada à Saúde, Fundação Oswaldo Cruz, FIOCRUZ Rondônia, Porto Velho, RO, Brazil; Departamento de Medicina, Universidade Federal de Rondônia, UNIR, Porto Velho, RO, Brazil. Electronic address:
Toxins (Basel)
September 2024
Cardiovascular Research Team (UR5_3 PC2E), University of the French West Indies (Université des Antilles), 97200 Fort-de-France, France.
Background: Consumption coagulopathy and hemorrhagic syndrome are the typical features of sp. snake envenoming. In contrast, envenoming can induce thrombotic complications.
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