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Perioperative Management of Patients with Preeclampsia: A Comprehensive Review.
Anesthesiology
February 2025
Division of Obstetric Anesthesiology, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Preeclampsia is a common condition of pregnancy characterized by hypertension complicated by cerebral, cardiac, hepatic, renal, hematologic, and placental dysfunction. Patients with preeclampsia frequently undergo cesarean delivery, the most common major surgical procedure in the world. They represent a high-risk perioperative cohort suffering significant preventable morbidity and mortality.
View Article and Find Full Text PDFSignificance of Diagnostic Findings of Placenta Percreta by Magnetic Resonance Imaging and Pathological Correlation.
Cureus
December 2024
Radiology Department, Hospital Regional Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado Monterrey, Universidad de Monterrey, Monterrey, MEX.
Placenta percreta is a rare form of disorder found in the spectrum of placenta accreta and represents a considerable cause of maternal complications with an increase in mortality. The radiologist's role is essential due to the support of images acquired by magnetic resonance imaging, given their high sensitivity and specificity to predict the degree of placental invasion in substitution or accompaniment of the ultrasound study between 28 and 32 weeks of gestation. We present the case of a 29-year-old patient who was in her third pregnancy with a history of two cesarean sections at the ISSSTE Regional Hospital in Monterrey, Nuevo León.
View Article and Find Full Text PDFVisible and invisible cultural patterns influencing women's use of maternal health services among Igala women in Nigeria: a focused ethnographic study.
BMC Public Health
January 2025
College of Nursing, University of Saskatchewan, Health Science Building-1A10, 107 Wiggins Road, Box 6, Saskatoon, SK, Saskatchewan, S7N 5E5, Canada.
Background: Explicit and implicit cultural patterns are critical cultural norms, beliefs, and practices that determine women's health-seeking behaviour. These cultural patterns could limit women's use of maternal health services, resulting in maternal health complications. The study aims to provide an in-depth understanding of explicit and implicit cultural patterns, their meanings and how they influence women's use of maternal health services among Igala women in Nigeria.
View Article and Find Full Text PDFCasein Kinases 2-dependent phosphorylation of the placental ligand VAR2CSA regulates Plasmodium falciparum-infected erythrocytes cytoadhesion.
PLoS Pathog
January 2025
Sorbonne Université, CNRS, Inserm, Centre d'Immunologie et des Maladies Infectieuses, CIMI, Paris, France.
Placental malaria is characterized by the massive accumulation and sequestration of infected erythrocytes in the placental intervillous blood spaces, causing severe birth outcomes. The variant surface antigen VAR2CSA is associated with Plasmodium falciparum sequestration in the placenta via its capacity to adhere to chondroitin sulfate A. We have previously shown that the extracellular region of VAR2CSA is phosphorylated on several residues and that the phosphorylation enhances the adhesive properties of CSA-binding infected erythrocytes.
View Article and Find Full Text PDFMechanistic Target of Rapamycin Signaling Activity in the Human Placenta Across Gestation and in Maternal Obesity.
Biol Reprod
January 2025
Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, Aurora, CO USA.
The mechanistic target of rapamycin (mTOR) system is vital to placental development, formation, and function. Alterations in this system in the placenta have been associated with altered fetal growth. However, changes in placental mTOR signaling across gestation are poorly understood.
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