Unlabelled: The histological structure, distribution of neutral glycoseaminoglycanes, the content of glycogen in the cells, activity of succinate dehydrogenase, cytochromoxidase, magnesium-dependent ATP-ase, alkaline phosphatase, lactate dehydrogenase were studied in the biopsies of the gastric mucosa removed from the anterior third of the anterior part of its body in 104 patients.

Results: essential decrease of the enzymes of oxidative phosphorylation, increased reaction to lactate dehydrogenase, inhibition of enzymes controlling the microcirculation in the gastric mucosa in ulcer disease. These changes deteriorate in elderly patients as well as concomitant diseases of the hepatobiliary system.

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