Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Systems serology in cystic fibrosis: Anti-Pseudomonas IgG1 responses and reduced lung function.
Cell Rep Med
October 2023
Center for Translational Research in Infection and Inflammation, School of Medicine, Tulane University, New Orleans, LA, USA. Electronic address:
Nearly one-half of patients with cystic fibrosis (CF) carry the homozygous F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene but exhibit variable lung function phenotypes. How adaptive immunity influences their lung function remains unclear, particularly the serological antibody responses to antigens from mucoid Pseudomonas in sera from patients with CF with varying lung function. Sera from patients with CF with reduced lung function show higher anti-outer membrane protein I (OprI) immunoglobulin G1 (IgG1) titers and greater antibody-mediated complement deposition.
View Article and Find Full Text PDFPseudomonas aeruginosa Soluble Pyocins as Antibacterial Weapons.
Methods Mol Biol
October 2023
Institut de Génétique et de Développement de Rennes (IGDR), CNRS UMR 6290, Université de Rennes, Rennes, France.
Pseudomonas aeruginosa is an opportunistic pathogen causing nosocomial infections and associated with lung infections in cystic fibrosis (CF) patients (Lyczak et al., Microbes Infect 2:1051-1060, 2000). Multiple drug-resistant P.
View Article and Find Full Text PDFIn-depth biological characterization of two black soldier fly anti- peptides reveals LPS-binding and immunomodulating effects.
mSphere
October 2023
Laboratory of Microbiology, Parasitology and Hygiene (LMPH), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium.
As effector molecules of the innate immune system, antimicrobial peptides (AMPs) have gathered substantial interest as a potential future generation of antibiotics. Here, we demonstrate the anti- activity and lipopolysaccharide (LPS)-binding ability of HC1 and HC10, two cecropin peptides from the black soldier fly (). Both peptides are active against a wide range of strains, including drug-resistant clinical isolates.
View Article and Find Full Text PDFAnti- activity of natural antimicrobial peptides when used alone or in combination with antibiotics.
Front Microbiol
September 2023
Department of Pharmacy, China-Japan Friendship Hospital, Beijing, China.
The World Health Organization has recently published a list of 12 drug-resistant bacteria that posed a significant threat to human health, and () was among them. In China, is a common pathogen in hospital acquired pneumonia, accounting for 16.9-22.
View Article and Find Full Text PDFDevelopment of an anti- therapeutic monoclonal antibody WVDC-5244.
Front Cell Infect Microbiol
May 2023
Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, United States.
The rise of antimicrobial-resistant bacterial infections is a crucial health concern in the 21st century. In particular, antibiotic-resistant causes difficult-to-treat infections associated with high morbidity and mortality. Unfortunately, the number of effective therapeutic interventions against antimicrobial-resistant infections continues to decline.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!